Evidence map›Paper›PMID 30257445›Full record

ReviewMolecules (Basel, Switzerland)2018

Oligosaccharides Derived from Red Seaweed: Production, Properties, and Potential Health and Cosmetic Applications.

Kit-Leong Cheong, Hua-Mai Qiu, Hong Du, Yang Liu, Bilal Muhammad Khan

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Commercial importance of seaweeds: an overview.Bioresources and bioprocessing · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Revealing the Potential ofMarine drugs · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Recent progress inFood chemistry: X · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kit-Leong CheongGuangdong Provincial Key Laboratory of Marine Biotechnology, STU-UNIVPM Joint Algal Research Center, Department of Biology, College of Science, Shantou University, Shantou 515063, China. klcheong@stu.edu.cn.ORCID 0000-0001-8380-0123
Hua-Mai QiuGuangdong Provincial Key Laboratory of Marine Biotechnology, STU-UNIVPM Joint Algal Research Center, Department of Biology, College of Science, Shantou University, Shantou 515063, China. 18hmqiu@stu.edu.cn.
Hong DuGuangdong Provincial Key Laboratory of Marine Biotechnology, STU-UNIVPM Joint Algal Research Center, Department of Biology, College of Science, Shantou University, Shantou 515063, China. hdu@stu.edu.cn.
Yang LiuGuangdong Provincial Key Laboratory of Marine Biotechnology, STU-UNIVPM Joint Algal Research Center, Department of Biology, College of Science, Shantou University, Shantou 515063, China. liuyanglft@stu.edu.cn.
Bilal Muhammad KhanGuangdong Provincial Key Laboratory of Marine Biotechnology, STU-UNIVPM Joint Algal Research Center, Department of Biology, College of Science, Shantou University, Shantou 515063, China. khan@stu.edu.cn.ORCID 0000-0002-0564-6164

Funding

Cultivation Fund of Shantou University NTF17001Department of Education of Guangdong Province 2017KQNCX077National Natural Science Foundation of China 81741167Natural Science Foundation of Guangdong Province 2018A030310151Research and Development Start-up Foundation of Shantou University NTF16014
6 · The paper itself

Abstract

Because of their potential use as functional ingredients in human nutrition, oligosaccharides derived from natural sources are receiving paramount consideration. Red seaweed, a proven rich source of agar and carrageenan, is one of the most abundantly present sources of such oligosaccharides. Agaro-oligosaccharides (AOS) and carrageenan-oligosaccharides (COS) are produced from agar and carrageenan, respectively, through chemical and enzymatic hydrolyses. Enzymatic hydrolysis of agar and carrageenan into oligosaccharides is preferred in industrial production because of certain problems associated with chemical hydrolysis, including the release of high amounts of monosaccharides and undesirable toxic products, such as furfural. AOS and COS possess many biological activities, including prebiotic, immuno-modulatory, anti-oxidant, and anti-tumor activities. These activities are related to their chemical structure, molecular weight, degree of polymerization, and the flexibility of the glycosidic linkages. Therefore, the structure⁻function relationship and the mechanisms occurring during the specific biological applications of AOS and COS are discussed herein. Moreover, the chromatographic separation, purification, and characterization of AOS and COS are also part of this review. This piece of writing strives to create a new perspective on the potential applications of AOS and COS in the functional food and pharmaceutical industry.

Indexed as

AgarAntioxidantsCarrageenanCosmeticsHumansHydrolysisOligosaccharidesPrebioticsSeaweedAgarAntioxidantsCarrageenanCosmeticsOligosaccharidesPrebioticsagaro-oligosaccharidesbiological activitiescarrageenan-oligosaccharidesred seaweed

Identifiers

PMID30257445
PMCPMC6222765

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.