Evidence map›Paper›PMID 30257260›Full record

ArticleApplied clinical informatics2018

Automated versus Manual Data Extraction of the Padua Prediction Score for Venous Thromboembolism Risk in Hospitalized Older Adults.

Juliessa M Pavon, Richard J Sloane, Carl F Pieper, Cathleen S Colón-Emeric, Harvey J Cohen, David Gallagher, Miriam C Morey, Midori McCarty, Thomas L Ortel, Susan N Hastings

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Applied clinical informatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. A real-time prognostic model for venous thromboembolic events among hospitalized adults.Research and practice in thrombosis and haemostasis · 2024
    Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Juliessa M PavonDuke University, Durham, North Carolina, United States.
Richard J SloaneDuke University, Durham, North Carolina, United States.
Carl F PieperDuke University, Durham, North Carolina, United States.
Cathleen S Colón-EmericDuke University, Durham, North Carolina, United States.
Harvey J CohenDuke University, Durham, North Carolina, United States.
David GallagherDuke University, Durham, North Carolina, United States.
Miriam C MoreyDuke University, Durham, North Carolina, United States.
Midori McCartyDuke University, Durham, North Carolina, United States.
Thomas L OrtelDuke University, Durham, North Carolina, United States.
Susan N HastingsDuke University, Durham, North Carolina, United States.
Duke University · USHealth Services Research & Development · US

Funding

Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Virginia B Kraus · 2006 to 2026
$24.6M
Mentoring Intervention Development in Fall and Fracture PreventionK24AG049077 · NIA · DUKE UNIVERSITY · PI COLON-EMERIC, CATHLEEN S · 2015 to 2019
$361k
Adherence to Venous Thromboembolism Prophylaxis Guidelines in Hospitalized EldersR03AG048007 · NIA · DUKE UNIVERSITY · PI PAVON, JULIESSA M · 2014 to 2015
$233k
NIA NIH HHS K24 AG049077NIA NIH HHS P30 AG028716NIA NIH HHS R03 AG048007
6 · The paper itself

Abstract

objectiveVenous thromboembolism (VTE) prophylaxis is an important consideration for hospitalized older adults, and the Padua Prediction Score (PPS) is a risk prediction tool used to prioritize patient selection. We developed an automated PPS (APPS) algorithm using electronic health record (EHR) data. This study examines the accuracy of APPS and its individual components versus manual data extraction.

methodsThis is a retrospective cohort study of hospitalized general internal medicine patients, aged 70 and over. Fourteen clinical variables were collected to determine their PPS; APPS used EHR data exports from health system databases, and a trained abstractor performed manual chart abstractions. We calculated sensitivity and specificity of the APPS, using manual PPS as the gold standard for classifying risk category (low vs. high). We also examined performance characteristics of the APPS for individual variables.

resultsPPS was calculated by both methods on 311 individuals. The mean PPS was 3.6 (standard deviation, 1.8) for manual abstraction and 2.8 (1.4) for APPS. In detecting patients at high risk for VTE, the sensitivity and specificity of the APPS algorithm were 46 and 94%, respectively. The sensitivity for APPS was poor (range: 6-34%) for detecting acute conditions (i.e., acute myocardial infarction), moderate (range: 52-74%) for chronic conditions (i.e., heart failure), and excellent (range: 94-98%) for conditions of obesity and restricted mobility. Specificity of the automated extraction method for each PPS variable was > 87%.

conclusionAPPS as a stand-alone tool was suboptimal for classifying risk of VTE occurrence. The APPS accurately identified high risk patients (true positives), but lower scores were considered indeterminate.

Indexed as

HospitalizationVenous ThromboembolismAgedAged, 80 and overAutomationData MiningFemaleHumansMaleRetrospective StudiesRisk Assessment

Identifiers

PMID30257260
PMCPMC6158031
OpenAlexW2893436330

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.