ArticleSocial cognitive and affective neuroscience2018
Early maternal care may counteract familial liability for psychopathology in the reward circuitry.
Article in Social cognitive and affective neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Parental Deprivation- and Threat-Based Factors Associated with Youth Emotion-Based Neurocircuitry and Externalizing Behavior: A Systematic Review.Research on child and adolescent psychopathology · 2024Pooled it
- Infant social interactions and brain development: A systematic review.Neuroscience and biobehavioral reviews · 2021Pooled it
- Parenting in Moments: An Ecological Momentary Assessment of Parenting and Adolescent Substance Use and Externalizing Behaviors.Social development (Oxford, England) · 2026Article
- Transdiagnostic divergent neural development of reward anticipation in early adolescents at risk for depression and psychosis.Developmental cognitive neuroscience · 2026Article
- Associations between perceived excessive maternal control in childhood, well-being, and dorsal striatum volume in older adults.Scientific reports · 2025Article
- Lifespan adversities affect neural correlates of behavioral inhibition in adults.Frontiers in psychiatry · 2024Article
- Effects of Parenting Environment on Child and Adolescent Social-Emotional Brain Function.Current topics in behavioral neurosciences · 2022Review
- Early maternal care and amygdala habituation to emotional stimuli in adulthood.Social cognitive and affective neuroscience · 2021Article
- [The domain "social processes" in the system of research domain criteria: current state and perspectives].Der Nervenarzt · 2021Review
- [Cohort studies in child and adolescent psychiatry].Der Nervenarzt · 2021Review
- Prediction Along a Developmental Perspective in Psychiatry: How Far Might We Go?Frontiers in systems neuroscience · 2021Review
- The correlation between family relationships and brain activity within the reward circuit in adolescents with Internet gaming disorder.Scientific reports · 2020Article
- Developmental trajectories to reduced activation of positive valence systems: A review of biological and environmental contributions.Developmental cognitive neuroscience · 2020Review
- Resilience and the brain: a key role for regulatory circuits linked to social stress and support.Molecular psychiatry · 2020Review
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reward processing is altered in various psychopathologies and has been shown to be susceptible to genetic and environmental influences. Here, we examined whether maternal care may buffer familial risk for psychiatric disorders in terms of reward processing. Functional magnetic resonance imaging during a monetary incentive delay task was acquired in participants of an epidemiological cohort study followed since birth (N = 172, 25 years). Early maternal stimulation was assessed during a standardized nursing/playing setting at the age of 3 months. Parental psychiatric disorders (familial risk) during childhood and the participants' previous psychopathology were assessed by diagnostic interview. With high familial risk, higher maternal stimulation was related to increasing activation in the caudate head, the supplementary motor area, the cingulum and the middle frontal gyrus during reward anticipation, with the opposite pattern found in individuals with no familial risk. In contrast, higher maternal stimulation was associated with decreasing caudate head activity during reward delivery and reduced levels of attention deficit hyperactivity disorder (ADHD) in the high-risk group. Decreased caudate head activity during reward anticipation and increased activity during delivery were linked to ADHD. These findings provide evidence of a long-term association of early maternal stimulation on both adult neurobiological systems of reward underlying externalizing behavior and ADHD during development.
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