ArticleJournal of experimental botany2019
CsMYB60 is a key regulator of flavonols and proanthocyanidans that determine the colour of fruit spines in cucumber.
Article in Journal of experimental botany, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 60 citations in OpenAlex.
- Transposon-mediated structural haplotypes at CsMYB60 are associated with peel coloration in cucumber.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- 5-Aminolevulinic acid improves strawberry salt tolerance through a NO-HJournal of advanced research · 2025Article
- Harnessing the MYB51/SWEET20 module to increase soybean yield by facilitating sugar supply to sink organs.Plant cell reports · 2025Article
- The development of ideal insertion and deletion (InDel) markers and initial indel map variation in cucumber using re-sequenced data.BMC genomics · 2025Article
- Uncovering the genetic mechanism of rind color trait in watermelon using fine mapping and comparative transcriptomic analysis.Frontiers in plant science · 2025Article
- Identification and functional analysis of GmPasL regulating pod color in vegetable soybean.BMC plant biology · 2024Article
- Genetic characterization of cucumber genetic resources in the NARO Genebank indicates their multiple dispersal trajectories to the East.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Impact of Climate Change on Regulation of Genes Involved in Sex Determination and Fruit Production in Cucumber.Plants (Basel, Switzerland) · 2023Review
- GhWRKY41 forms a positive feedback regulation loop and increases cotton defence response against Verticillium dahliae by regulating phenylpropanoid metabolism.Plant biotechnology journal · 2023Article
- Metabolomic and transcriptomic analyses reveal the effects of grafting on blood orange quality.Frontiers in plant science · 2023Article
- Fine mapping and identifying candidate gene ofFrontiers in plant science · 2023Article
- Morphological and Genetic Diversity of Cucumber (Plants (Basel, Switzerland) · 2022Review
- Integrated Analysis of Transcriptome and Metabolome Reveals New Insights into the Formation of Purple Leaf Veins and Leaf Edge Cracks inPlants (Basel, Switzerland) · 2022Article
- Transcriptomic and functional analysis provides molecular insights into multicellular trichome development.Plant physiology · 2022Article
- MdSCL8 as a Negative Regulator Participates in ALA-InducedInternational journal of molecular sciences · 2022Article
- Identification and characterization ofHorticulture research · 2022Article
- Quercetin Alleviates Lipopolysaccharide-Induced Inflammatory Response in Bovine Mammary Epithelial Cells by Suppressing TLR4/NF-κB Signaling Pathway.Frontiers in veterinary science · 2022Article
- A Systematic Phylogenomic Classification of the Multidrug and Toxic Compound Extrusion Transporter Gene Family in Plants.Frontiers in plant science · 2022Article
- Molecular research progress and improvement approach of fruit quality traits in cucumber.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Review
- Transcriptome profiling reveals response genes for downy mildew resistance in cucumber.Planta · 2021Article
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spine colour is an important fruit quality trait that influences the commercial value of cucumber (Cucumis sativus). However, little is known about the metabolites and the regulatory mechanisms of their biosynthesis in black spine varieties. In this study, we determined that the pigments of black spines are flavonoids, including flavonols and proanthocyanidins (PAs). We identified CsMYB60 as the best candidate for the previously identified B (Black spine) locus. Expression levels of CsMYB60 and the key genes involved in flavonoid biosynthesis were higher in black-spine inbred lines than that in white-spine lines at different developmental stages. The insertion of a Mutator-like element (CsMULE) in the second intron of CsMYB60 decreased its expression in a white-spine line. Transient overexpression assays indicated that CsMYB60 is a key regulatory gene and Cs4CL is a key structural gene in the pigmentation of black spines. In addition, the DNA methylation level in the CsMYB60 promoter was much lower in the black-spine line compared with white-spine line. The CsMULE insert may decrease the expression level of CsMYB60, causing hindered synthesis of flavonols and PAs in cucumber fruit spines.
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