ArticlePLoS genetics2018
Genetic basis of thermal plasticity variation in Drosophila melanogaster body size.
Article in PLoS genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Private QTLs and the genetic architecture of hierarchical size traits: from body size to sex-specific plasticity.G3 (Bethesda, Md.) · 2026Article
- A novel Hox gene promoter fuels the evolution of adaptive phenotypic plasticity in wing eyespots of satyrid butterflies.Nature ecology & evolution · 2025Article
- Carryover Effects on Reproduction Can Buffer Against Mortality-Driven Population Declines at Elevated Developmental Temperatures.Ecology letters · 2025Article
- Latitudinal Clines in Climate and Sleep Patterns Shape Disease Outcomes inEcology and evolution · 2025Article
- No degradation of temperature-mediated phenotypic plasticity inmicroPublication biology · 2025Article
- Body size decline during thermal evolution is only detected at mild temperature.Proceedings. Biological sciences · 2024Article
- Article
- The transcriptional state and chromatin landscape of cichlid jaw shape variation across species and environments.Molecular ecology · 2023Article
- Unveiling Subtle Geographical Clines: Phenotypic Effects and Dynamics of Circadian Clock Gene Polymorphisms.Biology · 2023Article
- Article
- Dynamics and stage-specificity of between-population gene expression divergence in the Drosophila melanogaster larval fat body.PLoS genetics · 2023Article
- Genomic Basis of Adaptation to a Novel Precipitation Regime.Molecular biology and evolution · 2023Article
- Effects of Wolbachia on Transposable Element Expression Vary Between Drosophila melanogaster Host Genotypes.Genome biology and evolution · 2023Article
- Within-population variation in body size plasticity in response to combined nutritional and thermal stress is partially independent from variation in development time.Journal of evolutionary biology · 2023Article
- Long-term evolution of quantitative traits in the Drosophila melanogaster species subgroup.Genetica · 2022Article
- Article
- A genome-wide analysis suggests pleiotropic effects of Green Revolution genes on shade avoidance in wheat.Evolutionary applications · 2022Article
- Genetic Background Matters: Population-Based Studies in Model Organisms for Translational Research.International journal of molecular sciences · 2022Review
- The genetic basis and adult reproductive consequences of developmental thermal plasticity.The Journal of animal ecology · 2022Article
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Body size is a quantitative trait that is closely associated to fitness and under the control of both genetic and environmental factors. While developmental plasticity for this and other traits is heritable and under selection, little is known about the genetic basis for variation in plasticity that can provide the raw material for its evolution. We quantified genetic variation for body size plasticity in Drosophila melanogaster by measuring thorax and abdomen length of females reared at two temperatures from a panel representing naturally segregating alleles, the Drosophila Genetic Reference Panel (DGRP). We found variation between genotypes for the levels and direction of thermal plasticity in size of both body parts. We then used a Genome-Wide Association Study (GWAS) approach to unravel the genetic basis of inter-genotype variation in body size plasticity, and used different approaches to validate selected QTLs and to explore potential pleiotropic effects. We found mostly "private QTLs", with little overlap between the candidate loci underlying variation in plasticity for thorax versus abdomen size, for different properties of the plastic response, and for size versus size plasticity. We also found that the putative functions of plasticity QTLs were diverse and that alleles for higher plasticity were found at lower frequencies in the target population. Importantly, a number of our plasticity QTLs have been targets of selection in other populations. Our data sheds light onto the genetic basis of inter-genotype variation in size plasticity that is necessary for its evolution.
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