ReviewJournal of neurophysiology2018
Pathway mechanism for excitatory and inhibitory control in working memory.
Review in Journal of neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Deciphering the Neural Effects of Emotional, Motivational, and Cognitive Challenges on Inhibitory Control Processes.Human brain mapping · 2025Article
- Cytoarchitectonic gradients of laminar degeneration in behavioural variant frontotemporal dementia.Brain : a journal of neurology · 2025Article
- Task-based effective connectivity finds alterations in frontoparietal network in Duchenne muscular dystrophy.Brain communications · 2025Article
- Computational modeling of attractor-based neural processes involved in the preparation of voluntary actions.Cognitive neurodynamics · 2024Article
- Timescales of learning in prefrontal cortex.Nature reviews. Neuroscience · 2024Review
- Slow wave activity disruptions and memory impairments in a mouse model of aging.Neurobiology of aging · 2024Article
- An optrode array for spatiotemporally-precise large-scale optogenetic stimulation of deep cortical layers in non-human primates.Communications biology · 2024Article
- Dynamic Network Connectivity: from monkeys to humans.Frontiers in human neuroscience · 2024Review
- Cortical type: a conceptual tool for meaningful biological interpretation of high-throughput gene expression data in the human cerebral cortex.Frontiers in neuroanatomy · 2023Article
- Thalamocortical Mechanisms Regulating the Relationship between Transient Beta Events and Human Tactile Perception.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- The effect of aging on context use and reliance on context in speech: A behavioral experiment with Repeat-Recall Test.Frontiers in aging neuroscience · 2022Article
- The prefrontal cortex, pathological anxiety, and anxiety disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
- Pathways for Contextual Memory: The Primate Hippocampal Pathway to Anterior Cingulate Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Muscarinic Acetylcholine Receptor Localization on Distinct Excitatory and Inhibitory Neurons Within the ACC and LPFC of the Rhesus Monkey.Frontiers in neural circuits · 2021Article
- NMDAR Neurotransmission Needed for Persistent Neuronal Firing: Potential Roles in Mental Disorders.Frontiers in psychiatry · 2021Review
- Laminar Differences in the Targeting of Dendritic Spines by Cortical Pyramidal Neurons and Interneurons in Human Dorsolateral Prefrontal Cortex.Neuroscience · 2021Article
- Serial Prefrontal Pathways Are Positioned to Balance Cognition and Emotion in Primates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Topological atlas of the hypothalamus in adult rhesus monkey.Brain structure & function · 2020Article
- Evolution of Brain Connections: Integrating Diffusion MR Tractography With Gene Expression Highlights Increased Corticocortical Projections in Primates.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Humans engage in many daily activities that rely on working memory, the ability to hold and sequence information temporarily to accomplish a task. We focus on the process of working memory, based on circuit mechanisms for attending to relevant signals and suppressing irrelevant stimuli. We discuss that connections critically depend on the systematic variation in laminar structure across all cortical systems. Laminar structure is used to group areas into types regardless of their placement in the cortex, ranging from low-type agranular areas that lack layer IV to high-type areas that have six well-delineated layers. Connections vary in laminar distribution and strength based on the difference in type between linked areas, according to the "structural model" (Barbas H, Rempel-Clower N. Cereb Cortex 7: 635-646, 1997). The many possible pathways thus vary systematically by laminar distribution and strength, and they interface with excitatory neurons to select relevant stimuli and with functionally distinct inhibitory neurons that suppress activity at the site of termination. Using prefrontal pathways, we discuss how systematic architectonic variation gives rise to diverse pathways that can be recruited, along with amygdalar and hippocampal pathways that provide sensory, affective, and contextual information. The prefrontal cortex is also connected with thalamic nuclei that receive the output of the basal ganglia and cerebellum, which may facilitate fast sequencing of information. The complement of connections and their interface with distinct inhibitory neurons allows dynamic recruitment of areas and shifts in cortical rhythms to meet rapidly changing demands of sequential components of working memory tasks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.