ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2018
Vasodilator function is impaired in burn injury survivors.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Post-burn Lung Inflammation Is Associated With Induction of Pulmonary Cathelicidin-related Antimicrobial Peptide and S100a8 in Mice.Journal of burn care & research : official publication of the American Burn Association · 2025Article
- Induced blood flow oscillations at 0.1 Hz protects oxygenation of severely ischemic tissue in humans.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Exercise Training Improves Microvascular Function in Burn Injury Survivors.Medicine and science in sports and exercise · 2020Article
- The benefits of an unsupervised exercise program in persons with well-healed burn injuries within the International Classification of Functioning, Disability and Health (ICF).Burns : journal of the International Society for Burn Injuries · 2020Article
- Article
- Acute lower leg hot water immersion protects macrovascular dilator function following ischaemia-reperfusion injury in humans.Experimental physiology · 2020Article
- Progressive exercise training improves maximal aerobic capacity in individuals with well-healed burn injuries.American journal of physiology. Regulatory, integrative and comparative physiology · 2019Article
- Editors' Picks for 2018 demonstrate the diversity of research in regulatory, integrative, and comparative physiology.American journal of physiology. Regulatory, integrative and comparative physiology · 2019Article
- Effects of punctate skin grafting combined with or without irrigation on skin graft survival, redness and swelling score and pain in treatment of large-area residual burn wounds.Pakistan journal of medical sciencesArticle
- Autologous fat grafting and adipose-derived stem cells therapy for acute burns and burn-related scar: A systematic review.Tzu chi medical journalArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The effect of severe burn injury on vascular health is unknown. We tested the hypothesis that, compared with nonburn control subjects, vasodilator function would be reduced and that pulse-wave velocity (a measure of arterial stiffness) would be increased in individuals with prior burn injuries, the extent of which would be associated with the magnitude of body surface area having sustained a severe burn. Pulse-wave velocity and macrovascular (flow-mediated dilation) and microvascular (reactive hyperemia) dilator functions were assessed in 14 nonburned control subjects and 32 age-matched subjects with well-healed burn injuries. Fifteen subjects with burn injuries covering 17-40% of body surface area were assigned to a moderate burn injury group, and 17 subjects with burn injuries covering >40% of body surface area were assigned to a high burn injury group. Pulse-wave velocity [ P = 0.3 (central) and P = 0.3 (peripheral)] did not differ between the three groups. Macrovascular dilator function was reduced in the moderate ( P = 0.07) and high ( P < 0.05) burn injury groups compared with the control group. Likewise, peak vascular conductance during postocclusive reactive hyperemia differed from the moderate burn injury group ( P = 0.08 vs. control) and the high burn injury group ( P < 0.05 vs. control). These data suggest that vasodilator function is impaired in well-healed burn injury survivors, with the extent of impairment not dependent on the magnitude of body surface area having sustained a severe burn injury.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.