ArticleMolecular and cellular biology1986
Multiple control elements in the TRP1 promoter of Saccharomyces cerevisiae.
Article in Molecular and cellular biology, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 46 citations in OpenAlex.
- The requirement of yeast replication origins for pre-replication complex proteins is modulated by transcription.Nucleic acids research · 2005Article
- SWI/SNF-dependent long-range remodeling of yeast HIS3 chromatin.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- HOY1, a homeo gene required for hyphal formation in Yarrowia lipolytica.Molecular and cellular biology · 1997Article
- Cloning and characterization of CSP37, a novel gene encoding a putative membrane protein of Candida albicans.Journal of bacteriology · 1997Article
- Aromatic amino acid biosynthesis in the yeast Saccharomyces cerevisiae: a model system for the regulation of a eukaryotic biosynthetic pathway.Microbiological reviews · 1991Review
- DNA binding of CPF1 is required for optimal centromere function but not for maintaining methionine prototrophy in yeast.Nucleic acids research · 1991Article
- Transcriptional activation by upstream activator sequences requires distinct interactions with downstream elements in the yeast TRP1 promoter.Molecular & general genetics : MGG · 1991Article
- SDC25, a CDC25-like gene which contains a RAS-activating domain and is a dispensable gene of Saccharomyces cerevisiae.Molecular and cellular biology · 1991Article
- CPF1, a yeast protein which functions in centromeres and promoters.The EMBO journal · 1990Article
- Overlapping reading frames at the LYS5 locus in the yeast Yarrowia lipolytica.Molecular and cellular biology · 1990Article
- Transcriptional control of the Saccharomyces cerevisiae PGK gene by RAP1.Molecular and cellular biology · 1989Article
- Characterization of the transcriptional potency of sub-elements of the UAS of the yeast PGK gene in a PGK mini-promoter.Nucleic acids research · 1989Article
- Functional relationship among TATA sequences, gene induction and transcription initiation in the beta-galactosidase, LAC4, gene from Kluyveromyces lactis.Current genetics · 1989Article
- Efficient activation of transcription in yeast by the BPV1 E2 protein.Nucleic acids research · 1989Article
- Multicopy plasmids containing the gene for the transcriptional activator LAC9 are not tolerated by K. lactis cells.Current genetics · 1989Article
- Identification of cDNA encoding an additional alpha subunit of a human GTP-binding protein: expression of three alpha i subtypes in human tissues and cell lines.Proceedings of the National Academy of Sciences of the United States of America · 1988Article
- A consensus transcription termination sequence in the promoter region is necessary for efficient gene expression of the TRP1 gene of Saccharomyces cerevisiae.Molecular & general genetics : MGG · 1988Article
- An AT rich region of dyad symmetry is a promoter element in the yeast TRP1 gene.Molecular & general genetics : MGG · 1988Article
- A heat shock element in the phosphoglycerate kinase gene promoter of yeast.Nucleic acids research · 1988Article
- Mutational analysis of upstream activation sequence 2 of the CYC1 gene of Saccharomyces cerevisiae: a HAP2-HAP3-responsive site.Molecular and cellular biology · 1988Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The TRP1 promoter generates two groups of mRNAs, transcript I and transcript II. The difference in size between the largest and smallest mRNAs is about 200 base pairs. A series of one-sided and internal deletions were constructed in vitro throughout the TRP1 promoter, and the effect of each deletion on transcription was assessed by Northern blotting. We showed that 395 base pairs of the TRP1 promoter were sufficient for the normal transcription of all RNAs and that the promoter contained two control domains. The control domain for transcript I consisted of one positive element and one negative element, while the control domain for transcript II contained two positive elements. The negative element, mapped between -293 and -318, expression of transcript I. Two regions of transcript I. Two regions (-280 to -236 and -235 to -209) were required for accurate initiation of transcript I. Each region contained sequences homologous to known consensus sequences of the TATA box.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.