Evidence map›Paper›PMID 30256437›Full record

ArticleJournal of cellular biochemistry2019

Sucrose nonfermenting AMPK-related kinase (SNARK) regulates exercise-stimulated and ischemia-stimulated glucose transport in the heart.

Xiang-Lan Sun, Sarah J Lessard, Ding An, Ho-Jin Koh, Hiroyasu Esumi, Michael F Hirshman, Laurie J Goodyear

Abstract read
In one paragraph

Article in Journal of cellular biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Xiang-Lan SunDepartment of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.ORCID 0000-0001-5123-1923
Sarah J LessardIntegrative Physiology and Metabolism Section, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Ding AnIntegrative Physiology and Metabolism Section, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Ho-Jin KohIntegrative Physiology and Metabolism Section, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Hiroyasu EsumiCancer Physiology Project, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Michael F HirshmanIntegrative Physiology and Metabolism Section, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Laurie J GoodyearIntegrative Physiology and Metabolism Section, Joslin Diabetes Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Joslin Diabetes Center · USNational Cancer Center Hospital East · JP

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI JEAN E. SCHAFFER · 1986 to 2026
$50.5M
ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTOPHER P DUGGAN · 1994 to 2026
$31.6M
Exercise Regulation of Glucose Homeostasis Administrative SupplementR01DK101043 · NIDDK · JOSLIN DIABETES CENTER · PI LAURIE J GOODYEAR · 2013 to 2026
$7.3M
Regultion of Serine/Threonine Kinases in Skeletal MuscleR01DK068626 · NIDDK · JOSLIN DIABETES CENTER · PI GOODYEAR, LAURIE J · 2004 to 2012
$3.5M
CIHR MFE‐83802NIDDK NIH HHS P30 DK036836NIDDK NIH HHS P30 DK040561NIDDK NIH HHS R01 DK068626NIDDK NIH HHS R01 DK101043
6 · The paper itself

Abstract

The signaling mechanisms mediating myocardial glucose transport are not fully understood. Sucrose nonfermenting AMP-activated protein kinase (AMPK)-related kinase (SNARK) is an AMPK-related protein kinase that is expressed in the heart and has been implicated in contraction-stimulated glucose transport in mouse skeletal muscle. We first determined if SNARK is phosphorylated on Thr

Indexed as

Physical Conditioning, AnimalAnimalsBiological TransportCell Line, TumorCoronary VesselsGene Knockdown TechniquesGlucoseInsulinIschemiaMaleMiceMice, Inbred ICRMice, KnockoutMyocardiumMyocytes, CardiacPhosphorylationGlucoseInsulinProtein Serine-Threonine KinasesSNARK protein, mouseAkt substrate of 160 kDaglycogenHL1 cardiomyocytesinsulin

Identifiers

PMID30256437
PMCPMC6347018
OpenAlexW2891888386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.