Evidence map›Paper›PMID 30256385›Full record

ArticleEpilepsia2018

Epilepsy-predictive magnetic resonance imaging changes following experimental febrile status epilepticus: Are they translatable to the clinic?

Megan M Curran, Elizabeth Haddad, Katelin P Patterson, Mankin Choy, Celine M Dubé, Tallie Z Baram, Andre Obenaus

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epilepsia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Vascular topology and blood flow are acutely impacted by experimental febrile status epilepticus.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  2. Article
  3. Review
  4. Quantitative TScientific reports · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Megan M CurranDepartment of Anatomy/Neurobiology, University of California, Irvine, Irvine, California.ORCID 0000-0003-3240-8310
Elizabeth HaddadDepartment of Pediatrics, University of California, Irvine, Irvine, California.
Katelin P PattersonDepartment of Anatomy/Neurobiology, University of California, Irvine, Irvine, California.
Mankin ChoyDepartment of Anatomy/Neurobiology, University of California, Irvine, Irvine, California.
Celine M DubéDepartment of Pediatrics, University of California, Irvine, Irvine, California.
Tallie Z BaramDepartment of Anatomy/Neurobiology, University of California, Irvine, Irvine, California.
Andre ObenausDepartment of Anatomy/Neurobiology, University of California, Irvine, Irvine, California.ORCID 0000-0003-0081-6950
University of California, Irvine · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008620 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GOLDIN, ALAN L · 1999 to 2023
$8.1M
Research_ProjectU54HD090257 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI GUAY-WOODFORD, LISA MARIE · 2016 to 2020
$5.9M
Epilepsy Research Training ProgramT32NS045540 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Tallie Z. Baram, Robert F Hunt · 2003 to 2026
$4.9M
FEBRILE SEIZURE MODEL--NEURONAL INJURY AND MECHANISMSR01NS035439 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARAM, TALLIE Z. · 1997 to 2018
$3.2M
Febrile Seizure Model - Neuronal Injury and MechanismsR37NS035439 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARAM, TALLIE Z. · 2006 to 2012
$2.6M
Cognitive Deficits After Experimental Febrile Seizures: Neurobiology & BiomarkersR01NS108296 · NINDS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BARAM, TALLIE Z., HOLMES, GREGORY L. · 2018 to 2022
$2.6M
Cognitive Deficits After Experimental Febrile Seizures: Neurobiology & BiomarkersR01NS078279 · NINDS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BARAM, TALLIE Z., HOLMES, GREGORY L. · 2011 to 2015
$1.7M
NICHD NIH HHS U54 HD090257NIGMS NIH HHS GM008620NIGMS NIH HHS T32 GM008620NINDS NIH HHS NS45540NINDS NIH HHS R01 NS035439NINDS NIH HHS R01 NS078279NINDS NIH HHS R01 NS108296NINDS NIH HHS R37 NS035439NINDS NIH HHS R37/RO1 NS35439NINDS NIH HHS T32 NS045540
6 · The paper itself

Abstract

objectiveA subset of children with febrile status epilepticus (FSE) are at risk for development of temporal lobe epilepsy later in life. We sought a noninvasive predictive marker of those at risk that can be identified soon after FSE, within a clinically realistic timeframe.

methodsLongitudinal T

resultsEpilepsy-predicting T SIGNIFICANCE: Early T

Indexed as

Disease ProgressionImage Processing, Computer-AssistedAnimalsAnimals, NewbornBrainDisease Models, AnimalElectroencephalographyFemaleFeverMagnetic Resonance ImagingMaleRatsRats, Sprague-DawleyROC CurveStatus EpilepticusTime Factorsepileptogenesisfebrile seizuresfebrile status epilepticusmagnetic resonance imagingtemporal lobe epilepsy

Identifiers

PMID30256385
PMCPMC6217797
OpenAlexW2891406297

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.