Evidence map›Paper›PMID 30255709›Full record

ArticleJournal of diabetes science and technology2019

Glycemic Control Maintained over Time and Joint Stiffness in Young Type 1 Patients: What Is the Mathematical Relationship?

Piergiorgio Francia, Michele Sorelli, Barbara Piccini, Giulia Iannone, Laura Capirchio, Sonia Toni, Massimo Gulisano, Leonardo Bocchi

Open access · bronzeAbstract read
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In one paragraph

Article in Journal of diabetes science and technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Piergiorgio Francia1 Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy.
Michele Sorelli2 Department of Information Engineering, University of Florence, Florence, Italy.
Barbara Piccini3 Diabetes Unit, Meyer Children's Hospital, Florence, Italy.
Giulia Iannone4 ANIMO, National Association of Movement Sciences, Florence, Italy.
Laura Capirchio3 Diabetes Unit, Meyer Children's Hospital, Florence, Italy.
Sonia Toni3 Diabetes Unit, Meyer Children's Hospital, Florence, Italy.
Massimo Gulisano1 Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy.
Leonardo Bocchi2 Department of Information Engineering, University of Florence, Florence, Italy.
University of Florence · ITMeyer Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is widely known that diabetes can induce stiffness and adversely affect joint mobility even in young patients with type 1 diabetes mellitus (T1D). The aim of this study was to identify a mathematical model of diabetes mellitus long-term effects on young T1D patients.

methodsAnkle joint mobility (AJM) was evaluated using an inclinometer in 48 patients and 146 healthy, sex- BMI-, and age-matched controls. Assuming time invariance and linear superposition of the effects of hyperglycemia, the influence of T1D on AJM was formalized as an impulse response putting into relationship past supernormal HbA1c concentrations with the ankle total range of motion. The proposed model was identified by means of a nonlinear evolutionary optimization algorithm.

resultsAJM was significantly reduced in young T1D patients (

conclusionsIn young patients with T1D the lack of glycemic control over time affects AJM. HbA1c levels can serve as a relevant prognostic factor for assessing the progression of LJM in subjects with diabetes.

Indexed as

Blood GlucoseModels, TheoreticalAdolescentAnkle JointDiabetes Mellitus, Type 1FemaleGlycated HemoglobinHumansMaleRange of Motion, ArticularBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanankle jointdiabetes mellitus type 1glycemic controllimited joint mobilitymathematical model

Identifiers

PMID30255709
PMCPMC6610591
OpenAlexW2893725010

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.