SynthesisSleep & breathing = Schlaf & Atmung2019
The prevalence of obstructive sleep apnea and its association with pregnancy-related health outcomes: a systematic review and meta-analysis.
Synthesis in Sleep & breathing = Schlaf & Atmung, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 6 syntheses or guidelines pooled it, 119 citations in OpenAlex.
- Diagnostic Accuracy of the Screening Questionnaires for Obstructive Sleep Apnoea in Pregnancy: A Meta-Analysis and Updated Systematic Review.Journal of sleep research · 2026Pooled it
- Effects of mind-body therapies on sleep quality in perinatal women: a systematic review and meta-analysis of randomized controlled trials.Frontiers in public health · 2026Pooled it
- Effect of the maternal sleep disturbances and obstructive sleep apnea on feto-placental Doppler: A systematic review.Journal of sleep research · 2025Pooled it
- Estimation of sleep problems among pregnant women during COVID-19 pandemic: a systematic review and meta-analysis.BMJ open · 2022Pooled it
- An umbrella review of systematic reviews and meta-analyses of observational investigations of obstructive sleep apnea and health outcomes.Sleep & breathing = Schlaf & Atmung · 2022Pooled it
- The invisible costs of obstructive sleep apnea (OSA): Systematic review and cost-of-illness analysis.PloS one · 2022Pooled it
- A Position Modification Device for the Prevention of Supine Sleep During Pregnancy: A Randomised Crossover Trial.BJOG : an international journal of obstetrics and gynaecology · 2025Trial
- Sleep-disordered Breathing in Pregnancy and after Delivery: Associations with Cardiometabolic Health.American journal of respiratory and critical care medicine · 2022Trial
- Questionnaire-Based Assessment of Obstructive Sleep Apnea Risk During Pregnancy: Associations with Metabolic Parameters and Family History of Diabetes.Healthcare (Basel, Switzerland) · 2026Article
- Development and validation of machine learning models for obstructive sleep apnea risk stratification in high-risk pregnant women.BMC pregnancy and childbirth · 2026Observational
- Influence of Obstructive Sleep Apnea on Maternal and Perinatal Outcomes in Patients With Gestational Diabetes Mellitus.Journal of sleep research · 2026Article
- Insomnia and women: exploring vulnerability, impact, and intervention.Sleep & breathing = Schlaf & Atmung · 2026Review
- Obstructive Sleep Apnea in Critically Ill Patients: A Structured Narrative Review of Prevalence, Diagnostic Barriers, and Clinical Implications in the ICU.Clocks & sleep · 2026Review
- Article
- Gestational Obstructive Sleep Apnea: From Pathophysiological Mechanisms to Maternal-Fetal Outcomes.Cureus · 2026Review
- Sleep and fatigue complaints during pregnancy versus perinatal depression: Impact on toddler cognition.Journal of affective disorders · 2026Article
- Psychometric Properties of the Chinese Version of the Ford Insomnia Response to Stress Test (FIRST-C) Among Pregnant Women in Qinghai Province, China: A Cross-Sectional Validation Study with Measurement Invariance Testing.International journal of women's health · 2026Article
- Ischemic Placental Disease and Severe Morbidity in Pregnant Patients With Sleep Disorders.JAMA network open · 2025Article
- Obstructive sleep apnea-associated hypertensive disorders in pregnancy: a literature review and clinical management strategies.Reproductive biology and endocrinology : RB&E · 2025Review
- Obstructive Sleep Apnea Syndrome in women: gender in sleep respiratory medicine is a first step towards personalized medicine.Sleep & breathing = Schlaf & Atmung · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeObstructive sleep apnea (OSA) is common during pregnancy. Nevertheless, prevalence estimates of OSA have varied widely due to variabilities in the assessment methods. This meta-analysis aimed to examine the prevalence of objectively assessed OSA and its association with pregnancy-related health outcomes in pregnant women.
methodsThis review was developed following the PRISMA guideline. A systematic search was conducted in major electronic databases to identify studies conducted from inception to January 2018. The pooled estimates with 95% confidence interval were calculated using the inverse variance method. Forest plots were used to present the results of individual studies and the pooled effect sizes.
resultsThirty-three studies were included. The mean gestational age was between 21.2 (8.5) and 37.3 (2.1) weeks. The pooled worldwide prevalence of OSA was 15% (95% CI 12-18%). The prevalence estimates ranged from 5% in the European Region to 20% in the Region of Americas. The prevalence estimates for different trimesters ranged from 15 to 19%. OSA was related to an increased risk for gestational hypertension, gestational diabetes, pre-eclampsia, C-section, postoperative wound complication, and pulmonary edema. The pooled adjusted odds ratio (aOR) values were 1.97, 1.55, 2.35, 1.42, 1.87, and 6.35, respectively. OSA was also related to an increased risk for preterm birth (aOR = 1.62) and neonatal intensive care unit admission (aOR = 1.28).
conclusionsOSA is a common health issue in pregnant women. OSA is associated with various pregnancy-related health outcomes. Routine screening, early diagnosis, and effective treatment of OSA are recommended in pregnant women, particularly during mid and late pregnancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.