Evidence map›Paper›PMID 30255440›Full record

GuidelineJournal of nephrology2018

Management of hepatitis C virus infection in patients with chronic kidney disease: position statement of the joint committee of Italian association for the study of the liver (AISF), Italian society of internal medicine (SIMI), Italian society of infectious and tropical disease (SIMIT) and Italian society of nephrology (SIN).

Roberto Minutolo, Alessio Aghemo, Antonio Chirianni, Fabrizio Fabrizi, Loreto Gesualdo, Edoardo G Giannini, Paolo Maggi, Vincenzo Montinaro, Ernesto Paoletti, Marcello Persico and 10 more

Open access · bronzeAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Journal of nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 12 institutions in 1 country.

Roberto MinutoloDivision of Nephrology, Department of Scienze Mediche, Chirurgiche, Neurologiche, Metaboliche e dell'Invecchiamento, University of Campania "Luigi Vanvitelli", Via M. Longo 50, 80138, Naples, Italy. roberto.minutolo@unicampania.it.ORCID http://orcid.org/0000-0001-5686-2089
Alessio AghemoDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Antonio ChirianniThird Department of Infectious Diseases Azienda Ospedaliera Ospedali dei Colli, Naples, Italy.
Fabrizio FabriziDivision of Nephrology, Maggiore Hospital and IRCCS Foundation, Milan, Italy.
Loreto GesualdoDivision of Nephrology, Azienda Ospedaliero-Universitaria Policlinico di Bari, Bari, Italy.
Edoardo G GianniniGastroenterology Unit, Department of Internal Medicine, University of Genoa, Genoa, Italy.
Paolo MaggiInfectious Disease Clinic, University of Bari, Bari, Italy.
Vincenzo MontinaroDivision of Nephrology, Azienda Ospedaliero-Universitaria Policlinico di Bari, Bari, Italy.
Ernesto PaolettiNephrology, Dialysis, and Transplantation, University of Genoa and Policlinico San Martino, Genoa, Italy.
Marcello PersicoInternal Medicine and Hepatology Unit, AOU San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy.
Francesco PerticoneDepartment of Medical and Surgical Sciences, University Magna Græcia, Catanzaro, Italy.
Salvatore PettaGastroenterology and Hepatology Unit, Di.Bi.M.I.S., University of Palermo, Palermo, Italy.
Massimo PuotiDivision of Infectious Diseases, Niguarda Cà Granda Hospital, Milan, Italy.
Giovanni RaimondoDepartment of Medicina Clinica e Sperimentale, University of Messina, Messina, Italy.
Maria RendinaDepartment of Emergency and Organ Transplantation, Section of Gastroenterology, University Hospital, Bari, Italy.
Anna Linda ZignegoDepartment of Experimental and Clinical Medicine, Interdepartmental Hepatology Center MaSVE, University of Florence, Florence, Italy.
Italian Society of Nephrology (SIN)
Italian Association for the Study of the Liver (AISF)
Italian Society of Infectious and Tropical Disease (SIMIT)
Italian Society of Internal Medicine (SIMI)
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITHumanitas University · ITOspedale Maggiore · ITOspedale Policlinico San Martino · ITUniversity of Bari Aldo Moro · ITUniversity of Messina · ITAzienda Universitaria Ospedaliera Consorziale - Policlinico Bari · ITMagna Graecia University · ITOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Florence · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) infection is now considered a systemic disease due to the occurrence of extra-hepatic manifestations. Among these, the renal involvement is frequent. HCV infection, in fact, is strongly associated with proteinuria and chronic kidney disease (CKD) and negatively affects the prognosis of renal patients. In the last few years, availability of more specific and effective drugs against HCV has dramatically changed the clinical course of this disease. These drugs may provide further advantages in the CKD population as a whole by reducing progression of renal disease, mortality rate and by increasing the survival of graft in renal transplant recipients. The strict pathogenetic and prognostic link between HCV infection and CKD requires an ongoing relationship among the healthcare professionals involved in the treatment of both HCV infection and CKD. Therefore, Scientific Societies involved in the care of this high-risk population in Italy have organized a joint expert panel. The aim of the panel is to produce a position statement that can be used in daily clinical practice for the management of HCV infected patients across the whole spectrum of renal disease, from the conservative phase to renal replacement treatments (dialysis and transplantation). Sharing specific evidence-based expertise of different professional healthcare is the first step to obtain a common ground of knowledge on which to instate a model for multidisciplinary management of this high-risk population. Statements cover seven areas including epidemiology of CKD, HCV-induced glomerular damage, HCV-related renal risk, staging of liver disease in patients with CKD, prevention of transmission of HCV in hemodialysis units, treatment of HCV infection and management of HCV in kidney transplantation.

Indexed as

Kidney TransplantationRenal DialysisAntiviral AgentsConsensusEvidence-Based MedicineHepacivirusHepatitis C, ChronicHumansPrevalenceRenal Insufficiency, ChronicRisk AssessmentRisk FactorsTreatment OutcomeAntiviral AgentsChronic kidney diseaseDirect-acting antiviral agentsHCV infectionHCV in renal transplantation

Identifiers

PMID30255440
OpenAlexW3023463001

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.