Evidence map›Paper›PMID 30255439›Full record

ArticleEJNMMI physics2018

Impact of a Bayesian penalized likelihood reconstruction algorithm on image quality in novel digital PET/CT: clinical implications for the assessment of lung tumors.

Michael Messerli, Paul Stolzmann, Michèle Egger-Sigg, Josephine Trinckauf, Stefano D'Aguanno, Irene A Burger, Gustav K von Schulthess, Philipp A Kaufmann, Martin W Huellner

Abstract read
In one paragraph

Article in EJNMMI physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

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  7. Impact of respiratory motion onJournal of applied clinical medical physics · 2023
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  8. A retrospective evaluation of Bayesian-penalized likelihood reconstruction for [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
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  11. Prognostic value of genetic alterations andAmerican journal of cancer research · 2023
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  14. Article
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  17. Influences on PET Quantification and Interpretation.Diagnostics (Basel, Switzerland) · 2022
    Review
  18. [European radiology · 2022
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michael MesserliDepartment of Nuclear Medicine, University Hospital Zurich/University of Zurich, Ramistrasse 100, 8091, Zurich, Switzerland. michael.messerli@usz.ch.
Paul StolzmannDepartment of Nuclear Medicine, University Hospital Zurich/University of Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.
Michèle Egger-SiggDepartment of Pathology and Molecular Pathology, University Hospital Zurich/University of Zurich, Zurich, Switzerland.
Josephine TrinckaufDepartment of Nuclear Medicine, University Hospital Zurich/University of Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.
Stefano D'AguannoGE Medical Systems (Schweiz) AG, Glattbrugg, Switzerland.
Irene A BurgerDepartment of Nuclear Medicine, University Hospital Zurich/University of Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.
Gustav K von SchulthessDepartment of Nuclear Medicine, University Hospital Zurich/University of Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.
Philipp A KaufmannDepartment of Nuclear Medicine, University Hospital Zurich/University of Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.
Martin W HuellnerDepartment of Nuclear Medicine, University Hospital Zurich/University of Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.

Funding

GE Healthcare Institutional grants from GE Healthcare (unrelated to current study)
6 · The paper itself

Abstract

backgroundThe aim of this study was to evaluate and compare PET image reconstruction algorithms on novel digital silicon photomultiplier PET/CT in patients with newly diagnosed and histopathologically confirmed lung cancer. A total of 45 patients undergoing 18F-FDG PET/CT for initial lung cancer staging were included. PET images were reconstructed using ordered subset expectation maximization (OSEM) with time-of-flight and point spread function modelling as well as Bayesian penalized likelihood reconstruction algorithm (BSREM) with different β-values yielding a total of 7 datasets per patient. Subjective and objective image assessment with all image datasets was carried out, including subgroup analyses for patients with high dose (> 2.0 MBq/kg) and low dose (≤ 2.0 MBq/kg) of 18F-FDG injection regimen.

resultsSubjective image quality ratings were significantly different among all different reconstruction algorithms as well as among BSREM using different β-values only (both p < 0.001). BSREM with a β-value of 600 was assigned the highest score for general image quality, image sharpness, and lesion conspicuity. BSREM reconstructions resulted in higher SUV

conclusionsBSREM reconstruction algorithm used in digital detector PET leads to significant increases of lung tumor SUV

Indexed as

Image quality enhancementImage reconstructionLung cancerPET/CTPositron-emission tomography

Identifiers

PMID30255439
PMCPMC6156690

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.