ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2019
Update on laboratory diagnosis of amoebiasis.
Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 122 citations in OpenAlex.
- Use of PCR in the diagnosis of pericardial amebiasis: a case report and systematic review of the literature.BMC infectious diseases · 2021Pooled it
- Giardia duodenalis and Entamoeba spp.: Coprological and antibody-based approaches across farm animals in Egypt.BMC veterinary research · 2026Article
- Gastrointestinal Parasites in Humans and Rhesus Macaques: A Cross-Sectional Study in Bhaktapur, Nepal.Health science reports · 2025Article
- Serodiagnosis of amoebic abscess: a retrospective diagnostic accuracy study of kits marketed in Europe.Journal of clinical microbiology · 2025Article
- Prevalence of intestinal parasitic infections for six years (2015-2020) in Thi-Qar Province, Iraq.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025Article
- Evaluation of Each ThreeMicroorganisms · 2025Article
- Three Autochthonous Cases of Amoebic Liver Abscess Clustered in a Small Village of Tuscany (Central Italy), a Non-Endemic Area.Pathogens (Basel, Switzerland) · 2025Article
- Trichomoniasis and Other Sexually Transmitted Parasitic Diseases in Women.Clinical obstetrics and gynecology · 2025Review
- Molecular prevalence and associated risk factors of Entamoeba spp. in donkeys in Shanxi Province, North China.Parasites & vectors · 2025Article
- Recent advances in the diagnosis and management of amoebiasis.Frontline gastroenterology · 2025Review
- A proof-of-concept point-of-care test for the serodiagnosis of human amebic liver abscess.PeerJ · 2025Article
- An Imported Case of Gigantic Amoebic Liver Abscess in a 24-Year-Old Woman in Singapore.Case reports in infectious diseases · 2025Article
- Molecular characterization of Giardia duodenalis, Cryptosporidium spp., and Entamoeba spp. infecting domestic and feral/stray cats in Jordan.Parasitology research · 2024Article
- Evaluation of Molecular Assays for Diagnosis of Amoebic Liver Abscess in India with Bayesian Latent Class Analysis.The American journal of tropical medicine and hygiene · 2024Article
- Electrochemical biosensors for the detection of protozoan parasite: a scoping review.Pathogens and global health · 2024Article
- Prevalence ofFood and waterborne parasitology · 2024Article
- Occult Amebiasis among Pediatric with Enterocolitis in National Referral Hospital in Indonesia.Infection & chemotherapy · 2024Article
- Molecular identification ofVeterinary world · 2024Article
- Amebic liver abscess: An update.World journal of hepatology · 2024Review
- Amoebic Liver Abscess: Potential Application of New Diagnostic Techniques for an Old Pathogen.Infectious diseases and therapy · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Amoebiasis, an enteric protozoan disease caused by Entamoeba histolytica, is a public health problem in many developing countries, causing up to 100,000 fatal cases annually. Detection of the pathogenic E. histolytica and its differentiation from the non-pathogenic Entamoeba spp. play a crucial role in the clinical management of patients. Laboratory diagnosis of intestinal amoebiasis in developing countries still relies on labour-intensive and insensitive methods involving staining of stool sample and microscopy. Newer and more sensitive methods include a variety of antigen detection ELISAs and rapid tests; however, their diagnostic sensitivity and specificity seem to vary between studies, and some tests do not distinguish among the Entamoeba species. Molecular detection techniques are highly sensitive and specific and isothermal amplification approaches may be developed into field-applicable tests; however, cost is still a barrier for their use as a routine laboratory test method in most endemic areas. Laboratory diagnosis of extraintestinal amoebiasis faces challenges of lack of definitive detection of current infection and commercially available point-of-care tests. For both types of amoebiasis, there is still a need for highly sensitive and specific tests that are rapid and cost-effective for use in developing countries where the disease is prevalent. In recent years, new molecules of diagnostic value are being discovered and new tests developed. The advances in 'omics' technologies are enabling discoveries of new biomarkers that may help distinguish between different infection stages.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.