ArticleSurgery today2019
Is neoadjuvant chemotherapy appropriate for patients with resectable liver metastases from colorectal cancer?
Article in Surgery today, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Impact of sequential perioperative chemotherapy for high-risk colorectal liver metastases.Surgery today · 2026Article
- Metachronous colorectal liver metastasis that occurred 10 years after laparoscopic colectomy: a case report.Surgical case reports · 2022Article
- Efficacy of neoadjuvant chemotherapy for initially resectable colorectal liver metastases: A retrospective cohort study.World journal of gastrointestinal oncology · 2022Article
- Neoadjuvant Chemotherapy Versus Upfront Surgery for Resectable Liver Metastases from Colorectal Cancer: a Multicenter, Propensity Score-Matched Cohort Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Treatment strategy for resectable colorectal cancer liver metastases from the viewpoint of time to surgical failure.Langenbeck's archives of surgery · 2022Article
- Oncological outcomes of neoadjuvant chemotherapy in patients with resectable synchronous colorectal liver metastasis: A result from a propensity score matching study.Frontiers in oncology · 2022Article
- Liver regeneration after extensive hepatectomy in rats: effect of preoperative chemotherapy with intravenous 5-fluorouracil.Acta cirurgica brasileira · 2022Article
- Efficacy of neoadjuvant chemotherapy in patients with high-risk resectable colorectal liver metastases.International journal of clinical oncology · 2021Article
- Neoadjuvant chemotherapy for patients with resectable colorectal cancer liver metastases: A systematic review and meta-analysis.World journal of clinical cases · 2021Article
- What is the optimal number of neoadjuvant chemotherapy cycles for resectable colorectal liver oligometastases?Annals of translational medicine · 2021Article
- Laparoscopic radical resection combined with neoadjuvant chemotherapy in treatment of colorectal cancer: clinical efficacy and postoperative complications.American journal of translational research · 2021Article
- From the completion of neoadjuvant chemotherapy to surgery for colorectal cancer liver metastasis: What is the optimal timing?Cancer medicine · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeNeoadjuvant chemotherapy (NAC) for resectable liver metastasis from colorectal cancer (CRLM) is used widely, but its efficacy lacks clear evidence. This study aimed to clarify its worth and develop appropriate treatment strategies for CRLM.
methodsWe analyzed, retrospectively, the clinicopathological factors and outcomes of 137 patients treated for resectable CRLM between 2006 and 2015, with upfront surgery (NAC
resultsThe time to surgical failure (TSF) and overall survival (OS) after initial treatment were significantly worse in the NAC
conclusionsPatients with resectable CRLM should undergo upfront hepatectomy because NAC did not improve OS after initial treatment in these patients.
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