ArticleEuropean radiology2019
Comparison of the diagnostic performance of CT Hounsfield unit histogram analysis and dual-energy X-ray absorptiometry in predicting osteoporosis of the femur.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- CT Hounsfield Unit Measurements Around the Hip and Their Utility for Opportunistic Screening: A Systematic Review.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Pooled it
- Pooled it
- Progress in machine learning-assisted medical imaging for osteoarthritis and osteoporosis diagnosis: a narrative review.Quantitative imaging in medicine and surgery · 2026Review
- BMI-stratified performance of native CT hounsfield units in the proximal femur for osteoporosis detection and fracture association.BMC musculoskeletal disorders · 2026Article
- [Trabecular bone density measurement in Hounsfield units in the proximal femur for osteoporosis assessment and fracture risk determination].Orthopadie (Heidelberg, Germany) · 2026Article
- Diagnostic Value of Opportunistic CT-Based Bone Density Assessment in Patients with and Without Sacral Insufficiency Fractures.Diagnostics (Basel, Switzerland) · 2025Article
- Osteoporosis Assessment Using Bone Density Measurement in Hounsfield Units in the Femoral Native CT Cross-Section: A Comparison with Computed Tomography X-Ray Absorptiometry of the Hip.Diagnostics (Basel, Switzerland) · 2025Article
- Femoral osteoporosis prediction model using autosegmentation and machine learning analysis with PyRadiomics on abdomen-pelvic computed tomography (CT).Quantitative imaging in medicine and surgery · 2024Article
- Comparative evaluation of multiparametric lumbar MRI radiomic models for detecting osteoporosis.BMC musculoskeletal disorders · 2024Article
- Measurement of Hounsfield units on proximal femur computed tomography for predicting regional osteoporosis.Radiologie (Heidelberg, Germany) · 2023Article
- Feasibility of diagnosing osteoporosis using routine computed tomography scans for hip fractures: Correlation with histopathological diagnosis of head and neck regions.Acta orthopaedica et traumatologica turcica · 2023Article
- Fat quantification of the rotator cuff muscles using CT histogram analysis in comparison with Dixon MRI sequence.The British journal of radiology · 2023Article
- Low bone mineral density is associated with fatty liver disease and respiratory illness in a pediatric mortality sample.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Article
- Diagnosis of Osteoporosis by Quantifying Volumetric Bone Mineral Density of Lumbar Vertebrae Using Abdominal CT Images and Two-Compartment Model.Healthcare (Basel, Switzerland) · 2023Article
- Average Lumbar Hounsfield Units Predicts Osteoporosis-Related Complications Following Lumbar Spine Fusion.Global spine journal · 2022Article
- Comparison of HU histogram analysis and BMD for proximal femoral fragility fracture assessment: a retrospective single-center case-control study.European radiology · 2022Article
- Correlation between Hounsfield unit derived from head, thorax, abdomen, spine and pelvis CT and t-scores from DXA.Skeletal radiology · 2021Article
- CT Hounsfield unit and histogram analysis for differentiation of recent versus remote vertebral compression fractures.The British journal of radiology · 2021Article
- Article
- Exploratory models comparing ethiodized oil-glue and gold fiducials for bladder radiotherapy image-guidance.Physics and imaging in radiation oncology · 2021Article
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4 authors.
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Abstract
purposeTo evaluate the diagnostic performance of Hounsfield unit histogram analysis (HUHA) of precontrast abdominal-pelvic CT scans for predicting osteoporosis. MATERIALS AND
methodsThe study included 271 patients who had undergone dual X-ray absorptiometry (DXA) and abdominal-pelvic CT within 1 month. HUHA was measured using commercial 3D analysis software (Aquarius iNtuition v4.4.12
resultsWhen the femur T-score was used as the reference, the rs of HUHA-A and HUHA-G were 0.74 and -0.57, respectively. Other HUHA values had moderate to weak correlations (r = -0.33 to 0.27). The correlation of HUHA-A was significantly higher than that of HUHA-G (p = 0.03). The area under the curve (0.95) of HUHA-A differed significantly from that of HUHA-G (0.90; p < 0.01). A HUHA-A threshold ≥ 27.7% was shown to predict osteoporosis based on a sensitivity and specificity of 95.6% and 81.7%, respectively.
conclusionThe HUHA-A value of the femoral neck is closely related to osteoporosis and may help predict osteoporosis. KEY POINTS: • HUHA correlated strongly with the DXA femur T-score (HUHA-A, r = 0.74). • The diagnostic performance of HUHA for predicting osteoporosis (AUC = 0.95) was better than that of the average CT HU value (AUC = 0.91; p < 0.05). • HUHA may help predict osteoporosis and enable semi-quantitative measurement of changes in bone mineral density.
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