Evidence map›Paper›PMID 30255220›Full record

SynthesisNeuropsychology review2018

The Neural Substrate of Reward Anticipation in Health: A Meta-Analysis of fMRI Findings in the Monetary Incentive Delay Task.

Robin Paul Wilson, Marco Colizzi, Matthijs Geert Bossong, Paul Allen, Matthew Kempton, MTAC, Sagnik Bhattacharyya

Erratum issuedOpen access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neuropsychology review, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 109 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 10 pooled it
8.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 10 syntheses or guidelines pooled it, 201 citations in OpenAlex.

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  18. Lithium modulates striatal reward anticipation and prediction error coding in healthy volunteers.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Robin Paul WilsonDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK. robin.wilson@kcl.ac.uk.
Marco ColizziDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK.
Matthijs Geert BossongDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK.
Paul AllenDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK.
Matthew KemptonDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK.
MTAC
Sagnik BhattacharyyaDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK.
King's College London · GB

Funding

Neurochemical Endophenotype Responses to Pain-StressR01DA016423 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZUBIETA, JON-KAR · 2004 to 2007
$1.4M
Placebo Effects in Depression: Towards the Validation of BiomarkersK23MH108674 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PECINA, MARTA · 2016 to 2019
$690k
CHARACTERIZATION OF P120, A CANDIDATE TUMOR SUPPRESSORF32CA008915 · NCI · DANA-FARBER CANCER INSTITUTE · PI CHITTENDEN, THOMAS D · 1990 to 1992
–
Department of Health NIHR-CS-011-001Medical Research Council MC_PC_14105Medical Research Council MR/J008915/1Medical Research Council MR/J012149/1NIDA NIH HHS R01 DA016423NIMH NIH HHS K23 MH108674
6 · The paper itself

Abstract

The monetary incentive delay task breaks down reward processing into discrete stages for fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral anticipation. We meta-analysed data from 15 original whole-brain group maps (n = 346) and report extensive areas of relative activation and deactivation throughout the whole brain. For both anticipation of gain and loss we report robust activation of the striatum, activation of key nodes of the putative salience network, including anterior cingulate and anterior insula, and more complex patterns of activation and deactivation in the central executive and default networks. On between-group comparison, we found significantly greater relative deactivation in the left inferior frontal gyrus associated with incentive valence. This meta-analysis provides a robust whole-brain map of a reward anticipation network in the healthy human brain.

Indexed as

Magnetic Resonance ImagingRewardAnticipation, PsychologicalBrain MappingHumansMotivationNerve NetAnticipation or rewardfMRIHealthy adultsMeta-analysisMonetary incentive delay task

Identifiers

PMID30255220
PMCPMC6327084
OpenAlexW2892840228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.