ArticleInternational journal of veterinary science and medicine2017
Effects of Yunnan Baiyao on blood coagulation parameters in beagles measured using kaolin activated thromboelastography and more traditional methods.
Article in International journal of veterinary science and medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 9 citations in OpenAlex.
- Research Advances in Pharmacology, Safety, and Clinical Applications of Yunnan Baiyao, a Traditional Chinese Medicine Formula.Frontiers in pharmacology · 2021Review
- The effects of oral administration of Yunnan Baiyao on blood coagulation in beagle dogs as measured by kaolin-activated thromboelastography and buccal mucosal bleeding times.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2017Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Yunnan Baiyao is anecdotally widely used in veterinary medicine for its pro-coagulation properties. There are no studies determining its effect on clotting tests. The purpose of this study was to determine the effect of oral Yunnan Baiyao (YB) on hemostasis by measuring coagulation via kaolin activated citrated whole blood thromboelastography (TEG), prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, and d-dimers. The study was a prospective, randomized controlled crossover trial. Eight healthy University of Calgary owned beagles were treated orally with either Yunnan Baiyao or placebo every 12 h for 5 treatments. Blood was collected immediately before treatment, 2 h after the last treatment, and 24 h after the last treatment. TEG analysis was run 30 ± 5 min after blood collection. All other coagulation analyses were sent to a reference laboratory for further analysis. No treatment adverse effects were observed. Oral YB increased R-time significantly within the YB group, but the increase was still within canine reference ranges. No other changes were observed. Oral YB at the dosage and frequency administered in this study did not produce any significant improvement in hemostatic parameters. There is a need for further research and scientific evidence for YB use and dosage.
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