Evidence map›Paper›PMID 30255029›Full record

ArticleInternational journal of genomics2018

Common DNA Variants Accurately Rank an Individual of Extreme Height.

Corinne E Sexton, Mark T W Ebbert, Ryan H Miller, Meganne Ferrel, Jo Ann T Tschanz, Christopher D Corcoran, Alzheimer's Disease Neuroimaging Initiative, Perry G Ridge, John S K Kauwe

Open access · goldAbstract read
In one paragraph

Article in International journal of genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Corinne E SextonDepartment of Biology, Brigham Young University, Provo, UT 84602, USA.
Mark T W EbbertDepartment of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
Ryan H MillerDepartment of Oncological Sciences, University of Utah, Salt Lake City, UT 84112, USA.
Meganne FerrelDepartment of Biology, Brigham Young University, Provo, UT 84602, USA.
Jo Ann T TschanzDepartment of Psychology, Utah State University, Logan, UT, USA.
Christopher D CorcoranCenter for Epidemiologic Studies, Utah State University, Logan, UT, USA.
Alzheimer's Disease Neuroimaging Initiative
Perry G RidgeDepartment of Biology, Brigham Young University, Provo, UT 84602, USA.ORCID 0000-0001-6944-2753
John S K KauweDepartment of Biology, Brigham Young University, Provo, UT 84602, USA.ORCID 0000-0001-8641-2468
Brigham Young University · USUtah State University · USMayo Clinic in Florida · USUniversity of Southern California · USUniversity of Utah · US

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

Polygenic scores (or genetic risk scores) quantify the aggregate of small effects from many common genetic loci that have been associated with a trait through genome-wide association. Polygenic scores were first used successfully in schizophrenia and have since been applied to multiple phenotypes including multiple sclerosis, rheumatoid arthritis, and height. Because human height is an easily-measured and complex polygenic trait, polygenic height scores provide exciting insights into the predictability of aggregate common variant effect on the phenotype. Shawn Bradley is an extremely tall former professional basketball player from Brigham Young University and the National Basketball Association (NBA), measuring 2.29 meters (7'6

Identifiers

PMID30255029
PMCPMC6142724
OpenAlexW2889932967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.