Evidence map›Paper›PMID 30254992›Full record

ArticleObstetrics & gynecology science2018

Differential expression and methylation of integrin subunit alpha 11 and thrombospondin in the amnion of preterm birth.

Jae Young Yoo, Young-Ah You, Eun Jin Kwon, Mi Hye Park, Sunah Shim, Young Ju Kim

Open access · diamondAbstract read
In one paragraph

Article in Obstetrics & gynecology science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Fetal Membrane Epigenetics.Frontiers in physiology · 2020
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jae Young YooDepartment of Obstetrics and Gynecology, Ewha Womans University College of Medicine, Seoul, Korea.
Young-Ah YouDepartment of Obstetrics and Gynecology, Ewha Womans University College of Medicine, Seoul, Korea.
Eun Jin KwonDepartment of Obstetrics and Gynecology, Ewha Womans University College of Medicine, Seoul, Korea.
Mi Hye ParkDepartment of Obstetrics and Gynecology, Ewha Womans University College of Medicine, Seoul, Korea.
Sunah ShimDepartment of Obstetrics and Gynecology, Ewha Womans University College of Medicine, Seoul, Korea.
Young Ju KimDepartment of Obstetrics and Gynecology, Ewha Womans University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3153-3008
Ewha Womans University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate the association between preterm birth and epigenetic mechanisms in the amnion.

methodsWe examined the association between differentially methylated regions (DMRs) and differentially expressed genes (DEG) using a cytosine-phosphate-guanine methylation array and whole-transcriptome sequencing from the amnion (preterm birth, n=5; full term, n=5). We enrolled 35 participants for mRNA expression analysis and pyrosequencing: 16 full-term and 19 preterm subjects. We compared the association of integrin subunit alpha 11 (

resultsIn the preterm birth group, methylation of

conclusionMethylation of the

Indexed as

Gene expressionITGA11 proteinMethylationmRNAPreterm birthThrombospondin 2

Identifiers

PMID30254992
PMCPMC6137008
OpenAlexW2890362884

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.