Evidence map›Paper›PMID 30254962›Full record

ReviewWorld journal of clinical oncology2018

Oxytocin and cancer: An emerging link.

Ben Lerman, Trisheena Harricharran, Olorunseun O Ogunwobi

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of clinical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Multi-Modal Deep Learning-Based Model to Predict Burkitt Lymphoma Recurrence.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Oxytocin and oxygen: the evolution of a solution to the 'stress of life'.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
  11. Article
  12. Article
  13. Love and longevity: A Social Dependency Hypothesis.Comprehensive psychoneuroendocrinology · 2021
    Review
  14. Article
  15. Article
  16. Is Oxytocin "Nature's Medicine"?Pharmacological reviews · 2020
    Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ben LermanDepartment of Biological Sciences, Hunter College of the City University of New York, New York, NY 10065, United States.
Trisheena HarricharranDepartment of Biological Sciences, Hunter College of the City University of New York, New York, NY 10065, United States.
Olorunseun O OgunwobiDepartment of Biological Sciences, Hunter College of the City University of New York, New York, NY 10065, United States.
Creative Research Enterprises (United States) · USCornell University · US

Funding

Hunter-Weill T32 Transdisciplinary Research TrainingT32HL135465 · NHLBI · HUNTER COLLEGE · PI ANGULO, JESUS A, BOUTIN-FOSTER, CARLA · 2017 to 2021
$1.8M
NHLBI NIH HHS T32 HL135465
6 · The paper itself

Abstract

The neuropeptide hormone oxytocin, which is released from the posterior pituitary gland, is involved in a number of physiological processes. Understanding of its effects is gradually increasing due to new research in this area. While mostly recognized as a reproductive system hormone, oxytocin also regulates other organ systems such as the brain and cardiovascular system. Recently, research has focused on unraveling its involvement in cancer, and emerging evidence suggests a potential role for oxytocin as a cancer biomarker. This review summarizes observations linking oxytocin and cancer, with a special emphasis on prostate cancer, where it may promote cell proliferation. Research suggests that oxytocin effects may depend on cell type, concentration of the hormone, its interactions with other hormones in the microenvironment, and the precise localization of its receptor on the cell membrane. Future research is needed to further elucidate the involvement of oxytocin in cancer, and whether it could be a clinical cancer biomarker or therapeutic target.

Indexed as

CancerExerciseOxytocinPancreasProstate

Identifiers

PMID30254962
PMCPMC6153127
OpenAlexW2891258806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.