ArticleGynecology and minimally invasive therapy
Efficacy of Hormonal Therapies for Decreasing Uterine Volume in Patients with Adenomyosis.
Article in Gynecology and minimally invasive therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Evaluation of pharmacological interventions in the management of adenomyosis: a systematic review.European journal of clinical pharmacology · 2022Pooled it
- Efficacy of High-Intensity Focused Ultrasound Combined With GnRH-a for Adenomyosis: A Systematic Review and Meta-Analysis.Frontiers in public health · 2021Pooled it
- Effect of extended hormonal suppression in patients with adenomyosis undergoing embryo transfer.Frontiers in reproductive health · 2026Review
- Association of hemorrhagic shock and pulmonary embolism following the administration of dienogest in a patient diagnosed with adenomyosis.Radiology case reports · 2024Article
- The Role of Different Medical Therapies in the Management of Adenomyosis: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Shared Pathogenic and Therapeutic Characteristics of Endometriosis, Adenomyosis, and Endometrial Cancer: A Comprehensive Literature Review.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Pregnancy is associated with reduced progression of symptomatic adenomyosis: a retrospective pilot study.BMC pregnancy and childbirth · 2023Article
- Effects of duration of long-acting GnRH agonist downregulation on assisted reproductive technology outcomes in patients with adenomyosis: a retrospective cohort study.Frontiers in medicine · 2023Article
- Effect of GnRH-a pretreatment before frozen-thawed embryo transfer on pregnancy outcome of adenomyosis-associated infertile patients with 56 cmAnnals of translational medicine · 2022Article
- Review
- Uterine Adenomyosis: From Disease Pathogenesis to a New Medical Approach Using GnRH Antagonists.International journal of environmental research and public health · 2021Review
- Late presentation of extrauterine adenomyomas after laparoscopic morcellation at hysterectomy: a case report.BMC women's health · 2021Article
- Adenomyosis and Infertility-Review of Medical and Surgical Approaches.International journal of environmental research and public health · 2021Review
- Impact of Uterine Adenomyosis on Pregnancy Outcomes in Women UndergoingFrontiers in endocrinology · 2021Article
- Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations.Nature communications · 2019Observational
- [Progress on medical treatment in the management of adenomyosis].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2019Article
- The Art of Managing Infertile Patients with Adenomyosis.Gynecology and minimally invasive therapyArticle
- Effectiveness of Laparoscopic Adenomyomectomy on Perinatal Outcomes.Gynecology and minimally invasive therapyArticle
- An Alternative Treatment for Uterine Fibroids and Adenomyosis: High-intensity Focused Ultrasound.Gynecology and minimally invasive therapyArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectiveThe aim of this study is to evaluate the efficacy of hormonal therapies for inhibiting an increase in uterine volume in patients with adenomyosis.
designThis was retrospective cohort study.
settingThis study was conducted at Nippon Medical School Musashikosugi Hospital. PATIENTS: A total of 28 women diagnosed with adenomyosis using magnetic resonance imaging.
methodsAfter providing informed consent, patients were treated with gonadotropin-releasing hormone agonist (GnRHa group), a low-dose estrogen and progestin combination (LEP group), or dienogest (DNG group) for ≥16 weeks. Uterine volume was assessed using the formula for an ovoid; uterine volumes before and after 16 weeks of treatment were compared. A <5% increase in uterine volume at 16 weeks was considered to reflect inhibition of uterine volume increase and efficacy of the medication. We compared the efficacy rate among the groups.
resultsIn the GnRHa group, a significant reduction in uterine volume was noted, from 307.4 ± 230.1 to 177.9 ± 142.1 cm
conclusionWe conclude that the efficacy of GnRHa in reducing uterine volume should be considered when prescribing hormone therapy for adenomyosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.