Evidence map›Paper›PMID 30254710›Full record

ReviewDisease markers2018

Usefulness of EEG Techniques in Distinguishing Frontotemporal Dementia from Alzheimer's Disease and Other Dementias.

Raffaele Nardone, Luca Sebastianelli, Viviana Versace, Leopold Saltuari, Piergiorgio Lochner, Vanessa Frey, Stefan Golaszewski, Francesco Brigo, Eugen Trinka, Yvonne Höller

Open access · hybridAbstract readReview
In one paragraph

Review in Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
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  5. Functional Connectivity Is Dominated by Aperiodic, Rather Than Oscillatory, Coupling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Raffaele NardoneDepartment of Neurology, Franz Tappeiner Hospital, Merano, Italy.ORCID 0000-0001-5243-6760
Luca SebastianelliDepartment of Neurorehabilitation, Hospital of Vipiteno, Vipiteno, Italy.ORCID 0000-0001-6463-000X
Viviana VersaceDepartment of Neurorehabilitation, Hospital of Vipiteno, Vipiteno, Italy.
Leopold SaltuariDepartment of Neurorehabilitation, Hospital of Vipiteno, Vipiteno, Italy.
Piergiorgio LochnerDepartment of Neurology, Saarland University Medical Center, Homburg, Germany.ORCID 0000-0002-2101-6066
Vanessa FreyDepartment of Neurology, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria.
Stefan GolaszewskiDepartment of Neurology, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0002-2055-0072
Francesco BrigoDepartment of Neurology, Franz Tappeiner Hospital, Merano, Italy.ORCID 0000-0003-0928-1577
Eugen TrinkaDepartment of Neurology, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria.
Yvonne HöllerDepartment of Neurology, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0002-1727-8557
Paracelsus Medical University · ATSaarland University · DEUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical distinction of frontotemporal dementia (FTD) and Alzheimer's disease (AD) may be difficult. In this narrative review we summarize and discuss the most relevant electroencephalography (EEG) studies which have been applied to demented patients with the aim of distinguishing the various types of cognitive impairment. EEG studies revealed that patients at an early stage of FTD or AD displayed different patterns in the cortical localization of oscillatory activity across different frequency bands and in functional connectivity. Both classical EEG spectral analysis and EEG topography analysis are able to differentiate the different dementias at group level. The combination of standardized low-resolution brain electromagnetic tomography (sLORETA) and power parameters seems to improve the sensitivity, but spectral and connectivity biomarkers able to differentiate single patients have not yet been identified. The promising EEG findings should be replicated in larger studies, but could represent an additional useful, noninvasive, and reproducible diagnostic tool for clinical practice.

Indexed as

Alzheimer DiseaseDiagnosis, DifferentialElectroencephalographyFrontotemporal DementiaHumans

Identifiers

PMID30254710
PMCPMC6140274
OpenAlexW2892201537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.