ReviewInternational journal of biomaterials2018
The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials
Review in International journal of biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Time-Varying Low-Frequency Electromagnetic Fields and Endothelial Angiogenesis: From Early In Vitro Discoveries to Emerging Mechanisms.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026Review
- Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation.Journal of biomedical materials research. Part B, Applied biomaterials · 2026Review
- Enhanced Osteogenic and Neurogenic Differentiation of Dental Pulp Stem Cells by Micro-Current Stimulation and Chitosan-Poly(Ethylene Glycol) Blended Calcium Phosphate Cement.ACS applied bio materials · 2026Article
- Possible Synergies of Nanomaterial-Assisted Tissue Regeneration in Plasma Medicine: Mechanisms and Safety Concerns.Nanomaterials (Basel, Switzerland) · 2022Review
- Biophysical therapy using the pulsating electromagnetic field as adjunctive therapy for implant osseointegration - A review.National journal of maxillofacial surgery · 2022Review
- Pulsed electromagnetic fields after intramedullary nailing of tibial fractures: a case control study.International orthopaedics · 2021Article
- Biomimetic Composite Coatings for Activation of Titanium Implant Surfaces: Methodological Approach and In Vivo Enhanced Osseointegration.Micromachines · 2021Article
- Article
- Synergistic Effect of PVDF-Coated PCL-TCP Scaffolds and Pulsed Electromagnetic Field on Osteogenesis.International journal of molecular sciences · 2021Article
- Evaluation of pulsed electromagnetic field protocols in implant osseointegration: in vivo and in vitro study.Clinical oral investigations · 2021Article
- In vitro chondrogenic differentiation of human articular cartilage derived chondroprogenitors using pulsed electromagnetic field.Journal of clinical orthopaedics and trauma · 2021Article
- In Vitro Production of Calcified Bone Matrix onto Wool Keratin Scaffolds via Osteogenic Factors and Electromagnetic Stimulus.Materials (Basel, Switzerland) · 2020Article
- Role of pulsed electromagnetic fields after joint replacements.World journal of orthopedics · 2020Review
- Response to: Comment on "The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials In Vitro and In Vivo".International journal of biomaterials · 2020Article
- The combinatory effect of sinusoidal electromagnetic field and VEGF promotes osteogenesis and angiogenesis of mesenchymal stem cell-laden PCL/HA implants in a rat subcritical cranial defect.Stem cell research & therapy · 2019Article
- Current Trends in Fabrication of Biomaterials for Bone and Cartilage Regeneration: Materials Modifications and Biophysical Stimulations.International journal of molecular sciences · 2019Review
- Comment on "The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to BiomaterialsInternational journal of biomaterials · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Implantable biomaterials are extensively used to promote bone regeneration or support endosseous prosthesis in orthopedics and dentistry. Their use, however, would benefit from additional strategies to improve bone responses. Pulsed Electromagnetic Fields (PEMFs) have long been known to act on osteoblasts and bone, affecting their metabolism, in spite of our poor understanding of the underlying mechanisms. Hence, we have the hypothesis that PEMFs may also ameliorate cell responses to biomaterials, improving their growth, differentiation, and the expression of a mature phenotype and therefore increasing the tissue integration of the implanted devices and their clinical success. A broad range of settings used for PEMFs stimulation still represents a hurdle to better define treatment protocols and extensive research is needed to overcome this issue. The present review includes studies that investigated the effects of PEMFs on the response of bone cells to different classes of biomaterials and the reports that focused on in vivo investigations of biomaterials implanted in bone.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.