Evidence map›Paper›PMID 30254507›Full record

ArticleMediators of inflammation2018

Dynamic DNA Methylation Changes of

Yiguo Qiu, Yunyun Zhu, Hongsong Yu, Chunjiang Zhou, Aize Kijlstra, Peizeng Yang

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. New perspectives on DNA methylation modifications in ocular diseases.International journal of ophthalmology · 2025
    Review
  5. Role of epigenetics in corneal health and disease.Progress in retinal and eye research · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Epigenetic Modifications and Therapy in Uveitis.Frontiers in cell and developmental biology · 2021
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yiguo QiuThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China.ORCID 0000-0002-9230-3206
Yunyun ZhuThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China.
Hongsong YuThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China.ORCID 0000-0002-1209-2104
Chunjiang ZhouThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China.
Aize KijlstraUniversity Eye Clinic Maastricht, Maastricht, Netherlands.
Peizeng YangThe First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China.ORCID 0000-0002-2647-6619
The Affiliated Yongchuan Hospital of Chongqing Medical University · CNMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The key transcription factors of T helper cell subpopulations, including T-bet, GATA3, ROR

Indexed as

AnimalsDNA (Cytosine-5-)-Methyltransferase 1DNA MethylationForkhead Transcription FactorsInterferon-gammaInterleukin-17MiceNuclear Receptor Subfamily 1, Group F, Member 3RetinaT-bet Transcription FactorT-Box Domain ProteinsUveitisDNA (Cytosine-5-)-Methyltransferase 1DNMT1 protein, humanForkhead Transcription FactorsFoxp3 protein, mouseInterferon-gammaInterleukin-17Nuclear Receptor Subfamily 1, Group F, Member 3Rorc protein, mouseT-bet Transcription FactorT-Box Domain Proteins

Identifiers

PMID30254507
PMCPMC6142759
OpenAlexW2890911396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.