Evidence map›Paper›PMID 30254454›Full record

ArticleOncoTargets and therapy2018

Podoplanin-positive cancer-associated fibroblasts predict poor prognosis in lung cancer patients.

Guoming Hu, Kefang Zhong, Wei Chen, Shimin Wang, Liming Huang

Abstract read
In one paragraph

Article in OncoTargets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Guoming HuDepartment of General Surgery (Breast and Thyroid Surgery), hgmplj@126.com; shaoxinghlm@126.com.
Kefang ZhongDepartment of General Surgery (Breast and Thyroid Surgery), hgmplj@126.com; shaoxinghlm@126.com.
Wei ChenDepartment of General Surgery (Breast and Thyroid Surgery), hgmplj@126.com; shaoxinghlm@126.com.
Shimin WangDepartment of Nephrology, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Zhejiang, China.
Liming HuangDepartment of General Surgery (Breast and Thyroid Surgery), hgmplj@126.com; shaoxinghlm@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer-associated fibroblasts (CAFs) are a heterogeneous population, and different subpopulations play differential roles in tumor microenvironment. However, the prognostic role of podoplanin-positive CAFs in human lung cancer still remains controversial.

methodsHerein, we performed a meta-analysis including 12 published studies with 1,802 patients identified from PubMed and EBSCO to assess the prognostic impact of podoplanin-positive CAFs in lung cancer patients.

resultsWe found that podoplanin

conclusionPodoplanin

Indexed as

lung cancermeta-analysispodoplanin-positive cancer-associated fibroblastsworse outcome

Identifiers

PMID30254454
PMCPMC6141120

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.