Evidence map›Paper›PMID 30254280›Full record

ArticleNature communications2018

Estimating sources and sinks of malaria parasites in Madagascar.

Felana Angella Ihantamalala, Vincent Herbreteau, Feno M J Rakotoarimanana, Jean Marius Rakotondramanga, Simon Cauchemez, Bienvenue Rahoilijaona, Gwenaëlle Pennober, Caroline O Buckee, Christophe Rogier, C J E Metcalf and 1 more

Abstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Genomics reveals heterogeneousmedRxiv : the preprint server for health sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Felana Angella IhantamalalaInstitut Pasteur de Madagascar, 101 Antanarivo, Madagascar.
Vincent HerbreteauUMR 228 ESPACE-DEV (IRD, UM2, UR, UAG), Station SEAS-Ol, Saint-Pierre, Reunion, France.ORCID http://orcid.org/0000-0003-1762-6336
Feno M J RakotoarimananaInstitut Pasteur de Madagascar, 101 Antanarivo, Madagascar.
Jean Marius RakotondramangaInstitut Pasteur de Madagascar, 101 Antanarivo, Madagascar.
Simon CauchemezMathematical Modeling of Infectious Diseases Unit, Institut Pasteur, Paris, 75015, France.
Bienvenue RahoilijaonaInstitut Pasteur de Madagascar, 101 Antanarivo, Madagascar.
Gwenaëlle PennoberUMR 228 ESPACE-DEV (IRD, UM2, UR, UAG), Station SEAS-Ol, Saint-Pierre, Reunion, France.
Caroline O BuckeeDepartment of Epidemiology, Harvard School of Public Health, Boston, MA, 02115, USA.
Christophe RogierUnité de recherche sur les maladies infectieuses et tropicales émergentes (URMITE), Paris, France.
C J E MetcalfDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, 08540, USA.ORCID http://orcid.org/0000-0003-3166-7521
Amy WesolowskiDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21231, USA. awesolowski@jhu.edu.ORCID http://orcid.org/0000-0001-6320-3575

Funding

Scientific and Technical Computing CoreP2CHD047879 · NICHD · PRINCETON UNIVERSITY · PI SALGANIK, MATTHEW J. · 2014 to 2018
$2.0M
Burroughs Wellcome Fund (BWF) Career Award at the Scientific InterfaceNICHD NIH HHS P2C HD047879Wellcome Trust
6 · The paper itself

Abstract

In areas where malaria epidemiology is spatially and temporally heterogeneous, human-mediated parasite importation can result in non-locally acquired clinical cases and outbreaks in low-transmission areas. Using mobility estimates derived from the mobile phone data and spatial malaria prevalence data, we identify travel routes relevant to malaria transmission in Madagascar. We find that the primary hubs of parasite importation are in a spatially connected area of the central highlands. Surprisingly, sources of these imported infections are not spatially clustered. We then related these source locations directly to clinical cases in the low-transmission area of the capital. We find that in the capital, a major sink, the primary sources of infection are along the more populated coastal areas, although these sources are seasonally variable. Our results have implications for targeting interventions at source locations to achieve local or national malaria control goals.

Indexed as

SeasonsTravelAnimalsCell PhoneGeographyHumansMadagascarMalariaPlasmodiumPopulation SurveillancePrevalence

Identifiers

PMID30254280
PMCPMC6156502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.