Evidence map›Paper›PMID 30254138›Full record

ReviewRNA (New York, N.Y.)2018

The multistructural forms of box C/D ribonucleoprotein particles.

Ge Yu, Yu Zhao, Hong Li

Abstract readReview
In one paragraph

Review in RNA (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Interprotomer communication and functional asymmetry in H/ACA snoRNPs.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Emergent microenvironments of nucleoli.Nucleus (Austin, Tex.) · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. The roles of NOP56 in cancer and SCA36.Pathology oncology research : POR · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ge YuDepartment of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida 32306, USA.
Yu ZhaoInstitute of Molecular Biophysics, Florida State University, Tallahassee, Florida 32306, USA.
Hong LiDepartment of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida 32306, USA.

Funding

Structures of RNA Processing and Silencing Enzymes in ProkaryotesR01GM099604 · NIGMS · FLORIDA STATE UNIVERSITY · PI STROUPE, M. ELIZABETH · 2012 to 2023
$3.3M
Structure and Regulation of snoRNP Interaction with rRNAR01GM066958 · NIGMS · FLORIDA STATE UNIVERSITY · PI LI, HONG · 2003 to 2012
$2.4M
Structural Biology Studies of Ribosome Biogenesis NetworkR01GM124622 · NIGMS · FLORIDA STATE UNIVERSITY · PI LI, HONG · 2018 to 2021
$1.7M
NIGMS NIH HHS R01 GM066958NIGMS NIH HHS R01 GM099604NIGMS NIH HHS R01 GM124622NIH HHS R01 GM099604NIH HHS R01 GM124622
6 · The paper itself

Abstract

Structural biology studies of archaeal and yeast box C/D ribonucleoprotein particles (RNPs) reveal a surprisingly wide range of forms. If form ever follows function, the different structures of box C/D small ribonucleoprotein particles (snoRNPs) may reflect their versatile functional roles beyond what has been recognized. A large majority of box C/D RNPs serve to site-specifically methylate the ribosomal RNA, typically as independent complexes. Select members of the box C/D snoRNPs also are essential components of the megadalton RNP enzyme, the small subunit processome that is responsible for processing ribosomal RNA. Other box C/D RNPs continue to be uncovered with either unexpected or unknown functions. We summarize currently known box C/D RNP structures in this review and identify the Nop56/58 and box C/D RNA subunits as the key elements underlying the observed structural diversity, and likely, the diverse functional roles of box C/D RNPs.

Indexed as

ArchaeaNuclear ProteinsNucleic Acid ConformationRibonucleoproteinsRibonucleoproteins, Small NucleolarRibosomesRNA, ArchaealRNA, RibosomalSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsNOP56 protein, S cerevisiaeNOP58 protein, S cerevisiaeNuclear ProteinsRibonucleoproteinsRibonucleoproteins, Small NucleolarRNA, ArchaealRNA, RibosomalSaccharomyces cerevisiae Proteinsfibrillarinkink-turnNop5Nop56Nop58ribosome biogenesisrRNA modificationsnoRNP structures

Identifiers

PMID30254138
PMCPMC6239191

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.