Evidence map›Paper›PMID 30254137›Full record

ArticleRNA (New York, N.Y.)2018

Divalent ions tune the kinetics of a bacterial GTPase center rRNA folding transition from secondary to tertiary structure.

Robb Welty, Suzette A Pabit, Andrea M Katz, George D Calvey, Lois Pollack, Kathleen B Hall

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Pressure pushes tRNAProceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Robb WeltyDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Suzette A PabitSchool of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA.
Andrea M KatzSchool of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA.
George D CalveySchool of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA.
Lois PollackSchool of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA.
Kathleen B HallDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Cornell University · USWashington University in St. Louis · US

Funding

Overall (pp. 40-62)P41GM103485 · NIGMS · CORNELL UNIVERSITY · PI CERIONE, RICHARD A. · 2012 to 2018
$15.5M
Nucleic acid interactions with partners: ions and proteinsR35GM122514 · NIGMS · CORNELL UNIVERSITY · PI Lois Pollack · 2017 to 2026
$3.8M
RNA folding: from global structure to atomic detailR01GM085062 · NIGMS · CORNELL UNIVERSITY · PI ELBER, RON, POLLACK, LOIS · 2009 to 2017
$2.7M
RNA-ligand interactions: simulation and experimentR01GM098102 · NIGMS · WASHINGTON UNIVERSITY · PI CHEATHAM, THOMAS E., HALL, KATHLEEN B · 2011 to 2014
$2.1M
NIGMS NIH HHS P41 GM103485NIGMS NIH HHS R01 GM085062NIGMS NIH HHS R01 GM098102NIGMS NIH HHS R35 GM122514
6 · The paper itself

Abstract

Folding of an RNA from secondary to tertiary structure often depends on divalent ions for efficient electrostatic charge screening (nonspecific association) or binding (specific association). To measure how different divalent cations modify folding kinetics of the 60 nucleotide

Indexed as

Cations, DivalentEscherichia coliGTP PhosphohydrolasesKineticsNucleic Acid ConformationRNA FoldingRNA, RibosomalScattering, Small AngleX-Ray DiffractionCations, DivalentGTP PhosphohydrolasesRNA, RibosomalkineticsRNA foldingrRNA GTPase centerSAXSstopped-flow fluorescence

Identifiers

PMID30254137
PMCPMC6239185
OpenAlexW2894016973

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.