Evidence map›Paper›PMID 30254025›Full record

ArticleJournal of cell science2018

Local microtubule organization promotes cargo transport in

Martin Harterink, Stacey L Edwards, Bart de Haan, Kah Wai Yau, Sander van den Heuvel, Lukas C Kapitein, Kenneth G Miller, Casper C Hoogenraad

Abstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Motor-Assisted Co-Migration of Intracellular Organelles and Microtubules as a Mechanism for Directed Cargo Transport.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. TheFrontiers in physiology · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin HarterinkCell Biology, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 Utrecht, The Netherlands m.harterink@uu.nl c.hoogenraad@uu.nl.ORCID 0000-0002-8256-6651
Stacey L EdwardsGenetic Models of Disease Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, US.
Bart de HaanCell Biology, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 Utrecht, The Netherlands.
Kah Wai YauCell Biology, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 Utrecht, The Netherlands.ORCID 0000-0003-1504-3604
Sander van den HeuvelDevelopmental Biology, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 Utrecht, The Netherlands.ORCID 0000-0001-9015-7463
Lukas C KapiteinCell Biology, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 Utrecht, The Netherlands.ORCID 0000-0001-9418-6739
Kenneth G MillerGenetic Models of Disease Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, US.
Casper C HoogenraadCell Biology, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 Utrecht, The Netherlands m.harterink@uu.nl c.hoogenraad@uu.nl.ORCID 0000-0002-2666-0758

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Signaling Pathways that Regulate Synaptic TransmissionR01GM080765 · NIGMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI MILLER, KENNETH GEORGE · 2007 to 2015
$2.7M
NIGMS NIH HHS R01 GM080765NIH HHS P40 OD010440
6 · The paper itself

Abstract

The specific organization of the neuronal microtubule cytoskeleton in axons and dendrites is an evolutionarily conserved determinant of neuronal polarity that allows for selective cargo sorting. However, how dendritic microtubules are organized and whether local differences influence cargo transport remains largely unknown. Here, we use live-cell imaging to systematically probe the microtubule organization in

Indexed as

AnimalsCaenorhabditis elegansCells, CulturedDendritesMicrotubulesProtein TransportC. elegansDendriteMicrotubuleMTOCPolarity

Identifiers

PMID30254025
PMCPMC6215390

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.