ArticleGenome biology2018
ABLE: blockwise site frequency spectra for inferring complex population histories and recombination.
Article in Genome biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Chromosome Fissions and Fusions Act as Barriers to Gene Flow between Brenthis Fritillary Butterflies.Molecular biology and evolution · 2023Article
- Graph-based algorithms for Laplace transformed coalescence time distributions.PLoS computational biology · 2022Article
- Nine out of ten samples were mistakenly switched by The Orang-utan Genome Consortium.Scientific data · 2022Article
- From molecules to populations: appreciating and estimating recombination rate variation.Nature reviews. Genetics · 2020Review
- Efficiently Summarizing Relationships in Large Samples: A General Duality Between Statistics of Genealogies and Genomes.Genetics · 2020Article
- Human Migration and the Spread of the Nematode Parasite Wuchereria bancrofti.Molecular biology and evolution · 2019Article
- Can genomics shed light on the origin of species?PLoS biology · 2019Article
- Article
- Practical considerations for plant phylogenomics.Applications in plant sciences · 2018Review
- Variation in recombination frequency and distribution across eukaryotes: patterns and processes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
We introduce ABLE (Approximate Blockwise Likelihood Estimation), a novel simulation-based composite likelihood method that uses the blockwise site frequency spectrum to jointly infer past demography and recombination. ABLE is explicitly designed for a wide variety of data from unphased diploid genomes to genome-wide multi-locus data (for example, RADSeq) and can also accommodate arbitrarily large samples. We use simulations to demonstrate the accuracy of this method to infer complex histories of divergence and gene flow and reanalyze whole genome data from two species of orangutan. ABLE is available for download at https://github.com/champost/ABLE .
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Registered trials
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