Evidence map›Paper›PMID 30253419›Full record

ArticleDigestive surgery2019

Liver Resection for Hepatic Metastases from Soft Tissue Sarcoma: A Nationwide Study.

Frederike A B Grimme, Maarten F J Seesing, Richard van Hillegersberg, Frits van Coevorden, Koert P de Jong, Iris D Nagtegaal, Cornelis Verhoef, Johannes H W de Wilt, On behalf of the Dutch Liver Surgery Working Group

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Digestive surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. MELANOMAS, SARCOMAS, AND RENAL METASTASES IN THE LIVER: HOW TO TREAT?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Low-grade fibromyxoid sarcoma of the liver: A case report.World journal of clinical cases · 2021
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Frederike A B GrimmeDepartment of Surgical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
Maarten F J SeesingDepartment of Surgical Oncology, University Medical Centre Utrecht, Cancer Center, Utrecht, The Netherlands.
Richard van HillegersbergDepartment of Surgical Oncology, University Medical Centre Utrecht, Cancer Center, Utrecht, The Netherlands.
Frits van CoevordenDepartment of Surgery, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Koert P de JongDepartment of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Iris D NagtegaalDepartment of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands.
Cornelis VerhoefDepartment of Surgical Oncology, Erasmus MC Cancer Institute Rotterdam, Rotterdam, The Netherlands.
Johannes H W de WiltDepartment of Surgical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands, Hans.deWilt@radboudumc.nl.
On behalf of the Dutch Liver Surgery Working Group
Radboud University Nijmegen · NLUniversity Medical Center Utrecht · NLErasmus MC Cancer Institute · NLRadboud University Medical Center · NLThe Netherlands Cancer Institute · NLUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to evaluate the feasibility and safety of resection of sarcoma liver metastases, and to identify possible prognostic factors for long-term survival.

methodsAll patients who underwent resection of liver metastases of sarcoma in the Netherlands from 1998 to 2014 were included. Study data was retrospectively collected from patient files. Survival rates were calculated using Kaplan-Meier survival analysis.

resultsSome 38 patients treated in 16 hospitals were included (15 male, 23 female). The median age was 57 years (37-80 years). The most common histological subtype was leiomyosarcoma (63%). The predominant site of primary tumour was the abdomen (59%). R0 resection was achieved in 16 patients. Mortality was 3 and 16% of included patients had 1 or more complications. The median follow-up period was 18 months (range 1-161). After liver resection, 1-, 3-, and 5-year survival were 88, 54, and 42% respectively. Median overall survival was 46 months (1-161 months). One- and three-year progression-free survival (PFS) after liver resection were 54 and 19% respectively. Median PFS was 16 months (1-61 months).

conclusionsLiver surgery for sarcoma metastases is safe and leads to a relatively good survival. The choice for surgical treatment should always be discussed in a multidisciplinary sarcoma and liver team.

Indexed as

HepatectomyAdultAgedAged, 80 and overFeasibility StudiesFemaleHumansKaplan-Meier EstimateLeiomyosarcomaLiver NeoplasmsMaleMiddle AgedNeoplasm, ResidualNetherlandsPostoperative ComplicationsProgression-Free SurvivalHepatic resectionLiver metastasisLiver resectionSarcoma

Identifiers

PMID30253419
PMCPMC6878742
OpenAlexW2892605982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.