Evidence map›Paper›PMID 30253084›Full record

ArticleBrain and behavior2018

The role of prefrontal cortex in a moral judgment task using functional near-infrared spectroscopy.

Hadis Dashtestani, Rachel Zaragoza, Riley Kermanian, Kristine M Knutson, Milton Halem, Aisling Casey, Nader Shahni Karamzadeh, Afrouz A Anderson, Albert Claude Boccara, Amir Gandjbakhche

Abstract read
In one paragraph

Article in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hadis DashtestaniSection on Analytical and Functional Biophotonics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Rachel ZaragozaSection on Analytical and Functional Biophotonics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Riley KermanianSection on Analytical and Functional Biophotonics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Kristine M KnutsonBrain Neurology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.
Milton HalemDepartment of Computer Science and Electrical Engineering, University of Maryland Baltimore County, Baltimore, Maryland.
Aisling CaseySection on Analytical and Functional Biophotonics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Nader Shahni KaramzadehSection on Analytical and Functional Biophotonics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Afrouz A AndersonSection on Analytical and Functional Biophotonics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Albert Claude BoccaraInstitut Langevin, ESPCI Paris, PSL Research University, Paris, France.
Amir GandjbakhcheSection on Analytical and Functional Biophotonics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.ORCID 0000-0003-2652-0162

Funding

Functional and Structural Optical Brain ImagingZIAHD008882 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI GANDJBAKHCHE, AMIR H · 2009 to 2025
$11.4M
6 · The paper itself

Abstract

backgroundUnderstanding the neural basis of moral judgment (MJ) and human decision-making has been the subject of numerous studies because of their impact on daily life activities and social norms. Here, we aimed to investigate the neural process of MJ using functional near-infrared spectroscopy (fNIRS), a noninvasive, portable, and affordable neuroimaging modality.

methodsWe examined prefrontal cortex (PFC) activation in 33 healthy participants engaging in MJ exercises. We hypothesized that participants presented with personal (emotionally salient) and impersonal (less emotional) dilemmas would exhibit different brain activation observable through fNIRS. We also investigated the effects of utilitarian and nonutilitarian responses to MJ scenarios on PFC activation. Utilitarian responses are those that favor the greatest good while nonutilitarian responses favor moral actions. Mixed effect models were applied to model the cerebral hemodynamic changes that occurred during MJ dilemmas. RESULTS AND

conclusionsOur analysis found significant differences in PFC activation during personal versus impersonal dilemmas. Specifically, the left dorsolateral PFC was highly activated during impersonal MJ when a nonutilitarian decision was made. This is consistent with the majority of relevant fMRI studies, and demonstrates the feasibility of using fNIRS, with its portable and motion tolerant capacities, to investigate the neural basis of MJ dilemmas.

Indexed as

MoralsAdolescentAdultDecision MakingEmotionsFemaleHemodynamicsHumansJudgmentMagnetic Resonance ImagingMaleMiddle AgedPrefrontal CortexSpectroscopy, Near-InfraredYoung Adultdorsolateral prefrontal cortexfunctional near-infrared spectroscopymixed effect modelmoral judgment

Identifiers

PMID30253084
PMCPMC6236239

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.