Evidence map›Paper›PMID 30252965›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2018

T-Cell-Mimicking Nanoparticles Can Neutralize HIV Infectivity.

Xiaoli Wei, Gang Zhang, Danni Ran, Nishta Krishnan, Ronnie H Fang, Weiwei Gao, Stephen A Spector, Liangfang Zhang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 198 citations in OpenAlex.

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  12. Red Blood Cell Membrane-Coated Nanoparticles Enable Incompatible Blood Transfusions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiaoli WeiDepartment of NanoEngineering and Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.
Gang ZhangDivision of Infectious Diseases, Department of Pediatrics, University of California San Diego, La Jolla, CA, 92093, USA.
Danni RanDepartment of NanoEngineering and Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.
Nishta KrishnanDepartment of NanoEngineering and Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.
Ronnie H FangDepartment of NanoEngineering and Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.
Weiwei GaoDepartment of NanoEngineering and Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.
Stephen A SpectorDivision of Infectious Diseases, Department of Pediatrics, University of California San Diego, La Jolla, CA, 92093, USA.
Liangfang ZhangDepartment of NanoEngineering and Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.ORCID https://orcid.org/0000-0003-0637-0654
University of California San Diego · US

Funding

Nanopeptide Targeting of HIV-CNS Reservoirs without ReactivationR01NS104015 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SPECTOR, STEPHEN A · 2017 to 2021
$2.9M
Modulating Autophagy to Eradicate HIV-1 from CNS ReservoirsR01NS084912 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SPECTOR, STEPHEN A · 2013 to 2017
$1.9M
Defense Threat Reduction Agency HDTRA1-14-1-0064National Institute of Neurological Disorders and Stroke R01NS104015NINDS NIH HHS R01 NS084912NINDS NIH HHS R01 NS104015
6 · The paper itself

Abstract

To improve human immunodeficiency virus (HIV) treatment and prevention, therapeutic strategies that can provide effective and broad-spectrum neutralization against viral infection are highly desirable. Inspired by recent advances of cell-membrane coating technology, herein, plasma membranes of CD4

Indexed as

CD4-Positive T-LymphocytesAnti-HIV AgentsBiomimetic MaterialsCell DeathCell LineHIV-1HIV Envelope Protein gp120HIV InfectionsHumansLeukocytes, MononuclearNanoparticlesRecombinant ProteinsAnti-HIV AgentsHIV Envelope Protein gp120Recombinant Proteinsantiretroviral therapybiomimetic nanoparticlecell membrane coatingHIVT cellviral neutralization

Identifiers

PMID30252965
PMCPMC6334303
OpenAlexW2893380545

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.