Evidence map›Paper›PMID 30252515›Full record

ArticleAmerican journal of public health2018

Sexual, Social, and Genetic Network Overlap: A Socio-Molecular Approach Toward Public Health Intervention of HIV.

Ethan Morgan, Britt Skaathun, John A Schneider

Abstract read
In one paragraph

Article in American journal of public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ethan MorganAll of the authors are with both the Department of Public Health Sciences and the Chicago Center for HIV Elimination, University of Chicago, Chicago, IL. John A. Schneider is also affiliated with the Department of Medicine, University of Chicago.
Britt SkaathunAll of the authors are with both the Department of Public Health Sciences and the Chicago Center for HIV Elimination, University of Chicago, Chicago, IL. John A. Schneider is also affiliated with the Department of Medicine, University of Chicago.
John A SchneiderAll of the authors are with both the Department of Public Health Sciences and the Chicago Center for HIV Elimination, University of Chicago, Chicago, IL. John A. Schneider is also affiliated with the Department of Medicine, University of Chicago.

Funding

Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/UM1AI068636 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, RAJESH T GANDHI · 2011 to 2026
$1073.1M
University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
HIV intervention models for criminal justice involved substance-using Black MSMR01DA039934 · NIDA · UNIVERSITY OF CHICAGO · PI FUJIMOTO, KAYO, HARAWA, NINA THAWATA · 2015 to 2019
$3.6M
Social Network Dynamics, HIV, and Risk Reduction Among Younger Black MSMR01DA033875 · NIDA · NATIONAL OPINION RESEARCH CENTER · PI SCHNEIDER, JOHN · 2012 to 2016
$3.0M
Digital communication networks in men at risk for HIVR21MH098768 · NIMH · UNIVERSITY OF CHICAGO · PI SCHNEIDER, JOHN · 2012 to 2013
$445k
NIAID NIH HHS P30 AI027757NIAID NIH HHS UM1 AI068636NIDA NIH HHS R01 DA033875NIDA NIH HHS R01 DA039934NIMH NIH HHS R21 MH098768
6 · The paper itself

Abstract

objectivesTo determine how network-level factors influence individual risk of HIV acquisition, which is key in preventing disease transmission.

methodsWe recruited a cohort of young Black men who have sex with men (n = 618) in Chicago, Illinois, from 2013 to 2016. We identified potential molecular ties via pairwise genetic distance analysis of HIV pol sequences with links inferred between individuals whose sequences were 1.5% or less genetically distant. We defined clusters as 1 or more connections to another individual. We conducted entity resolution between confidant, sexual, referral, and Facebook network data between network types.

resultsOf 266 (43.0%) participants identified as HIV-positive, we obtained 86 (32.3%) genetic sequences. Of these, 35 (40.7%) were linked to 1 or more other sequence; however, none of these were identified in first-, second-, or third-degree confidant and sexual networks. Minimal overlap existed between genetic and Facebook ties.

conclusionsThese results suggest that HIV transmissions may have occurred before elicitation of network data; future studies should expand the data collection timeframe to more accurately determine risk networks. Virtual network data, such as Facebook, may be particularly useful in developing one's risk environment.

Indexed as

AdolescentAdultBlack or African AmericanChicagoContact TracingDNA, ViralHIV-1HIV InfectionsHomosexuality, MaleHumansLongitudinal StudiesMaleRisk FactorsSequence Analysis, DNADNA, Viral

Identifiers

PMID30252515
PMCPMC6187777

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.