Evidence map›Paper›PMID 30252137›Full record

ArticleThe New phytologist2019

EFFECTOR OF TRANSCRIPTION factors are novel plant-specific regulators associated with genomic DNA methylation in Arabidopsis.

Francesca Tedeschi, Paride Rizzo, Bui Thi Mai Huong, Andreas Czihal, Twan Rutten, Lothar Altschmied, Sarah Scharfenberg, Ivo Grosse, Claude Becker, Detlef Weigel and 2 more

Open access · hybridAbstract read
In one paragraph

Article in The New phytologist, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  6. Taking the Wheel -Frontiers in plant science · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Francesca TedeschiLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Seeland OT Gatersleben, Germany.
Paride RizzoLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Seeland OT Gatersleben, Germany.
Bui Thi Mai HuongLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Seeland OT Gatersleben, Germany.
Andreas CzihalLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Seeland OT Gatersleben, Germany.
Twan RuttenLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Seeland OT Gatersleben, Germany.
Lothar AltschmiedLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Seeland OT Gatersleben, Germany.
Sarah ScharfenbergDepartment of Bioinformatics, Martin-Luther-University, 06120, Halle, Germany.
Ivo GrosseDepartment of Bioinformatics, Martin-Luther-University, 06120, Halle, Germany.
Claude BeckerDepartment of Molecular Biology, Max Planck Institute for Developmental Biology, 72076, Tübingen, Germany.
Detlef WeigelDepartment of Molecular Biology, Max Planck Institute for Developmental Biology, 72076, Tübingen, Germany.
Helmut BäumleinLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Seeland OT Gatersleben, Germany.
Markus KuhlmannLeibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Seeland OT Gatersleben, Germany.ORCID 0000-0003-3104-0825
Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK) · DEMartin Luther University Halle-Wittenberg · DEGregor Mendel Institute of Molecular Plant Biology · ATMax Planck Institute for Developmental Biology · DE

Funding

IPK Gatersleben (HB) BA1235/16-1IPK Gatersleben (HB) DFG SFB 1101the Max Planck Society FG project BA1235/16-1 (RKD)
6 · The paper itself

Abstract

Plant-specific EFFECTORS OF TRANSCRIPTION (ET) are characterised by a variable number of highly conserved ET repeats, which are involved in zinc and DNA binding. In addition, ETs share a GIY-YIG domain, involved in DNA nicking activity. It was hypothesised that ETs might act as epigenetic regulators. Here, methylome, transcriptome and phenotypic analyses were performed to investigate the role of ET factors and their involvement in DNA methylation in Arabidopsis thaliana. Comparative DNA methylation and transcriptome analyses in flowers and seedlings of et mutants revealed ET-specific differentially expressed genes and mostly independently characteristic, ET-specific differentially methylated regions. Loss of ET function results in pleiotropic developmental defects. The accumulation of cyclobutane pyrimidine dimers after ultraviolet stress in et mutants suggests an ET function in DNA repair.

Indexed as

DNA MethylationArabidopsisArabidopsis ProteinsEpigenesis, GeneticFlowersGene Expression Regulation, PlantMultigene FamilyMutationPhenotypePlants, Genetically ModifiedPyrimidine DimersSeedlingsTranscription FactorsUltraviolet RaysWhole Genome SequencingArabidopsis ProteinsET1 protein, ArabidopsisET2 protein, ArabidopsisPyrimidine DimersTranscription FactorsArabidopsis thalianaDNA methylationDNA repairEFFECTOR OF TRANSCRIPTION (ET)methylome

Identifiers

PMID30252137
PMCPMC6585611
OpenAlexW2894030801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.