Evidence map›Paper›PMID 30252104›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2020

Socioeconomic Status and Biological Risks for Health and Illness Across the Life Course.

Yang Claire Yang, Kristen Schorpp, Courtney Boen, Moira Johnson, Kathleen Mullan Harris

Open access · bronzeAbstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Add Health becomes an aging study: conceptualization, history and Wave VI design, response, and descriptive health data.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Who Reports Greater Chronic Disease Risk Behaviours? A Closer Look at Sociodemographic Differences Among Australian Adolescents: A Cross-Sectional Analysis.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2025
    Article
  11. Observational
  12. Article
  13. Article
  14. Impact of childhood and adult socioeconomic position on change in functional aging.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yang Claire YangDepartment of Sociology, University of North Carolina at Chapel Hill, Salem, Virginia.
Kristen SchorppDepartment of Sociology, Roanoke College, Salem, Virginia.
Courtney BoenDepartment of Sociology, University of Pennsylvania, Philadelphia.
Moira JohnsonDepartment of Sociology, University of North Carolina at Chapel Hill, Salem, Virginia.
Kathleen Mullan HarrisDepartment of Sociology, University of North Carolina at Chapel Hill, Salem, Virginia.
University of North Carolina at Chapel Hill · USRoanoke College · USUniversity City Science Center · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
U19 MIDlife in the United States-Diversity Supplement-WellsU19AG051426 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPHER L COE · 2016 to 2026
$74.8M
POPULATION STUDIEST32HD007168 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELIZABETH A FRANKENBERG · 1985 to 2026
$13.8M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Life Course Process of Alzheimer's Disease: Sex Difference and Biosocial MechanismsR01AG057800 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YANG, YANG CLAIRE · 2017 to 2021
$3.6M
NCI NIH HHS P30 CA016086NIA NIH HHS R01 AG057800NIA NIH HHS U19 AG051426NICHD NIH HHS P01 HD031921NICHD NIH HHS P2C HD050924NICHD NIH HHS R24 HD050924NICHD NIH HHS T32 HD007168
6 · The paper itself

Abstract

objectivesWe assess the temporal properties and biosocial mechanisms underlying the associations between early-life socioeconomic status (SES) and later health. Using a life-course design spanning adolescence to older adulthood, we assess how early life and various dimensions of adult SES are associated with immune and metabolic function in different life stages and examine possible bio-behavioral and psychosocial mechanisms underlying these associations.

methodData for this study come from 3 national studies that collectively cover multiple stages of the life course (Add Health, MIDUS, and HRS). We estimated generalized linear models to examine the prospective associations between early-life SES, adult SES, and biomarkers of chronic inflammation and metabolic disorder assessed at follow-up. We further conducted formal tests of mediation to assess the role of adult SES in linking early SES to biological functions.

resultsWe found that early-life SES exerted consistent protective effects for metabolic disorder across the life span, but waned with time for CRP. The protective effect of respondent education remained persistent for CRP but declined with age for metabolic disorder. Adult income and assets primarily protected respondents against physiological dysregulation in middle and old ages, but not in early adulthood. DISCUSSION: These findings are the first to elucidate the life-course patterns of SES that matter for underlying physiological functioning during the aging process to produce social gradients in health.

Indexed as

AgingSocial ClassAdolescentAdultAgedAged, 80 and overChildChronic DiseaseFemaleHumansInflammationLongitudinal StudiesMaleMetabolic SyndromeMiddle AgedProtective FactorsAgingInflammationLife courseMetabolic disorderPhysiological functioningSES

Identifiers

PMID30252104
PMCPMC7328029
OpenAlexW2893998109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.