ArticleAmerican journal of epidemiology2019
Associations of Prenatal Exposure to Cadmium With Child Growth, Obesity, and Cardiometabolic Traits.
Article in American journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Association of maternal exposure to trace elements and toxic metals with repeated measurements of foetal and early-childhood growth: a systematic review.Occupational and environmental medicine · 2025Pooled it
- Prenatal exposure to metal mixtures and the risk of overweight and obesity in school-aged children: insights from metabolomic profiling.Frontiers in nutrition · 2026Article
- As, Cd, Hg, and Pb Biological Concentrations and Anthropometry in Slovak Adolescents.Biological trace element research · 2025Article
- Metal mixture exposures and serum lipid levels in childhood: the Rhea mother-child cohort in Greece.Journal of exposure science & environmental epidemiology · 2024Article
- Prenatal Exposure to Heavy Metals and Adverse Birth Outcomes: Evidence From an E-Waste Area in China.GeoHealth · 2023Article
- Cadmium reduces growth of male fetuses by impairing development of the placental vasculature and reducing expression of nutrient transporters.Toxicology and applied pharmacology · 2023Article
- Lead, Mercury, and Cadmium Concentrations in Blood Products Transfused to Neonates: Elimination Not Just Mitigation.Toxics · 2023Article
- Effect of Cadmium on Oxidative Stress Indices and Vitamin D Concentrations in Children.Journal of clinical medicine · 2023Article
- Effect of umbilical cord essential and toxic elements, thyroid levels, and Vitamin D on childhood development.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023Article
- The inter- and multi- generational epigenetic alterations induced by maternal cadmium exposure.Frontiers in cell and developmental biology · 2023Review
- Food Safety Risks Posed by Heavy Metals and Persistent Organic Pollutants (POPs) related to Consumption of Sea Cucumbers.Foods (Basel, Switzerland) · 2022Review
- Lifestyle interventions to reduce endocrine-disrupting phthalate and phenol exposures among reproductive age men and women: A review and future steps.Environment international · 2022Review
- Perinatal Metal and Metalloid Exposures and Offspring Cardiovascular Health Risk.Current environmental health reports · 2022Review
- Heavy metal blood concentrations in association with sociocultural characteristics, anthropometry and anemia among Kenyan adolescents.International journal of environmental health research · 2022Article
- A metabolome-wide association study of in utero metal and trace element exposures with cord blood metabolome profile: Findings from the Boston Birth Cohort.Environment international · 2022Article
- Associations of exposure to cadmium, antimony, lead and their mixture with gestational thyroid homeostasis.Environmental pollution (Barking, Essex : 1987) · 2021Article
- Article
- Developmental toxicity of cadmium in infants and children: a review.Environmental analysis, health and toxicology · 2021Article
- Birth Cohorts in Highly Contaminated Sites: A Tool for Monitoring the Relationships Between Environmental Pollutants and Children's Health.Frontiers in public health · 2020Article
- Prenatal cadmium exposure is associated with shorter leukocyte telomere length in Chinese newborns.BMC medicine · 2019Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 5 countries.
Funding
Abstract
Prenatal cadmium exposure has been associated with impaired fetal growth; much less is known about the impact during later childhood on growth and cardiometabolic traits. To elucidate the associations of prenatal cadmium exposure with child growth, adiposity, and cardiometabolic traits in 515 mother-child pairs in the Rhea Mother-Child Study cohort (Heraklion, Greece, 2007-2012), we measured urinary cadmium concentrations during early pregnancy and assessed their associations with repeated weight and height measurements (taken from birth through childhood), waist circumference, skinfold thickness, blood pressure, and serum lipid, leptin, and C-reactive protein levels at age 4 years. Adjusted linear, Poisson, and mixed-effects regression models were used, with interaction terms for child sex and maternal smoking added. Elevated prenatal cadmium levels (third tertile of urinary cadmium concentration (0.571-2.658 μg/L) vs. first (0.058-0.314 μg/L) and second (0.315-0.570 μg/L) tertiles combined) were significantly associated with a slower weight trajectory (per standard deviation score) in all children (β = -0.17, 95% confidence interval (CI): -0.32, -0.02) and a slower height trajectory in girls (β = -0.30, 95% CI: -0.52,-0.09; P for interaction = 0.025) and in children born to mothers who smoked during pregnancy (β = -0.48, 95% CI: -0.83, -1.13; P for interaction = 0.027). We concluded that prenatal cadmium exposure was associated with delayed growth in early childhood. Further research is needed to understand cadmium-related sex differences and the role of coexposure to maternal smoking during early pregnancy.
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