Evidence map›Paper›PMID 30251958›Full record

ArticleTurkish journal of haematology : official journal of Turkish Society of Haematology2019

Investigation of the Relationship Between

Melek Erdem, Özlem Tüfekçi, Sefa Kızıldağ, Şebnem Yılmaz, Deniz Kızmazoğlu, Berna Eroğlu Filibeli, Hale Ören

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of haematology : official journal of Turkish Society of Haematology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Melek ErdemDokuz Eylül University Faculty of Medicine, Department of Pediatric Hematology, İzmir, TurkeyORCID 0000-0003-4273-7951
Özlem TüfekçiDokuz Eylül University Faculty of Medicine, Department of Pediatric Hematology, İzmir, TurkeyORCID 0000-0002-0721-1025
Sefa KızıldağDokuz Eylül University Faculty of Medicine, Department of Medical Biology, İzmir, TurkeyORCID 0000-0001-7939-5153
Şebnem YılmazDokuz Eylül University Faculty of Medicine, Department of Pediatric Hematology, İzmir, TurkeyORCID 0000-0001-7874-3734
Deniz KızmazoğluDokuz Eylül University Faculty of Medicine, Department of Pediatric Hematology, İzmir, TurkeyORCID 0000-0001-6269-187X
Berna Eroğlu FilibeliDokuz Eylül University Facullty of Medicine, Department of Pediatrics, İzmir, TurkeyORCID 0000-0002-2696-0195
Hale ÖrenDokuz Eylül University Faculty of Medicine, Department of Pediatric Hematology, İzmir, TurkeyORCID 0000-0001-5760-8007
Dokuz Eylül University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In acute lymphoblastic leukemia (ALL), various clinical risk factors and genetic predispositions contribute to the development of bone complications during and after chemotherapy. In this study, we aimed to investigate whether vitamin D receptor ( Materials and Methods: Fifty children with ALL who were treated with the ALL Berlin-Frankfurt-Muenster-95 protocol between 1998 and 2008 and were followed for at least 7 years were enrolled. The control group consisted of 96 healthy children. Results: Low BMD (16%), osteoporosis (12%), and osteonecrosis (8%) were present in a total of 18 patients (36%). The frequency of osteonecrosis and total bone abnormalities was significantly higher in children aged ≥10 years (p=0.001). The risk of low BMD and osteonecrosis was higher in those with vitamin D deficiency. Only the Conclusion: The development of therapy-induced bone mineral loss and osteonecrosis in children with ALL is frequent and the risk is especially higher in children aged ≥10 years and with vitamin D deficiency. The association between

Indexed as

Bone DensityChildChild, PreschoolCollagen Type ICollagen Type I, alpha 1 ChainFemaleGenetic Predisposition to DiseaseHumansInfantInfant, NewbornMaleOsteonecrosisOsteoporosisPolymorphism, GeneticPrecursor Cell Lymphoblastic Leukemia-LymphomaReceptors, CalcitriolCollagen Type ICollagen Type I, alpha 1 ChainReceptors, CalcitriolVDR protein, humanAcute lymphoblastic leukemiaBone mineral densityGenetic polymorphismOsteonecrosisOsteoporosis

Identifiers

PMID30251958
PMCPMC6373515
OpenAlexW2892430962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.