ArticleHuman brain mapping2019
The effects of individualised intermittent theta burst stimulation in the prefrontal cortex: A TMS-EEG study.
Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed.
- Theta burst stimulation of extrastriate body area for body perception in anorexia nervosa: a randomized controlled trial.Translational psychiatry · 2026Trial
- Altered activation in sensorimotor network after applying rTMS over the primary motor cortex at different frequencies.Brain and behavior · 2020Trial
- Theta burst stimulation for the treatment of obsessive-compulsive disorder: a pilot study.Journal of neural transmission (Vienna, Austria : 1996) · 2019Trial
- Personalized, EEG-controlled intermittent theta burst stimulation.medRxiv : the preprint server for health sciences · 2026Article
- Mapping the Digital Mind: A Meta-Analysis of EEG Biomarkers in Cognition, Emotion, and Mental Health.Brain sciences · 2026Review
- Neuroimaging-Guided Insights into the Molecular and Network Mechanisms of Chronic Pain and Neuromodulation.International journal of molecular sciences · 2026Review
- The Philadelphia Theta Burst Project: A novel fMRI-guided electric field modeling dataset with reliability metrics.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Potential neurophysiological mechanisms of intermittent theta-burst stimulation to the left prefrontal cortex for post-stroke unilateral neglect: An exploratory transcranial magnetic stimulation - electroencephalography study.IBRO neuroscience reports · 2025Article
- Assessing Neuromodulation Effects of Theta Burst Stimulation to the Prefrontal Cortex Using Transcranial Magnetic Stimulation Electroencephalography (TMS-EEG).The European journal of neuroscience · 2025Article
- Identifying neural circuitry abnormalities in neuropathic pain with transcranial magnetic stimulation and electroencephalogram co-registration.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Enhancing prefrontal modulation by phase-locking intermittent theta burst stimulation to a concurrent transcranial alternating current stimulation.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Differential analgesic effects of high-frequency or accelerated intermittent theta burst stimulation of M1 on experimental tonic pain: Correlations with cortical activity changes assessed by TMS-EEG.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024Article
- Accelerated Theta Burst Stimulation: Safety, Efficacy, and Future Advancements.Biological psychiatry · 2024Review
- Intermittent theta burst stimulation with synchronised transcranial alternating current stimulation leads to enhanced frontal theta oscillations and a positive shift in emotional bias.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- cTBS to Right DLPFC Modulates Physiological Correlates of Conflict Processing: Evidence from a Stroop task.Brain topography · 2024Article
- Personalized strategies of neurostimulation: from static biomarkers to dynamic closed-loop assessment of neural function.Frontiers in neuroscience · 2024Review
- Theta burst stimulation on the fronto-cerebellar connective network promotes cognitive processing speed in the simple cognitive task.Frontiers in human neuroscience · 2024Article
- Investigating the effects of excitatory and inhibitory somatosensory rTMS on somatosensory functioning in the acute and subacute phases of stroke: a preliminary double-blind and randomized trial.Frontiers in human neuroscience · 2024Article
- A dose-response characterization of transcranial magnetic stimulation intensity and evoked potential amplitude in the dorsolateral prefrontal cortex.Scientific reports · 2023Article
- Transcranial Magnetic Stimulation for the Treatment of Chemo Brain.Sensors (Basel, Switzerland) · 2023Article
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Authors and funding
7 authors.
Funding
Abstract
Recent studies have highlighted variability in response to theta burst stimulation (TBS) in humans. TBS paradigm was originally developed in rodents to mimic gamma bursts coupled with theta rhythms, and was shown to elicit long-term potentiation. The protocol was subsequently adapted for humans using standardised frequencies of stimulation. However, each individual has different rhythmic firing pattern. The present study sought to explore whether individualised intermittent TBS (Ind iTBS) could outperform the effects of two other iTBS variants. Twenty healthy volunteers received iTBS over left prefrontal cortex using 30 Hz at 6 Hz, 50 Hz at 5 Hz, or individualised frequency in separate sessions. Ind iTBS was determined using theta-gamma coupling during the 3-back task. Concurrent use of transcranial magnetic stimulation and electroencephalography (TMS-EEG) was used to track changes in cortical plasticity. We also utilised mood ratings using a visual analogue scale and assessed working memory via the 3-back task before and after stimulation. No group-level effect was observed following either 30 or 50 Hz iTBS in TMS-EEG. Ind iTBS significantly increased the amplitude of the TMS-evoked P60, and decreased N100 and P200 amplitudes. A significant positive correlation between neurophysiological change and change in mood rating was also observed. Improved accuracy in the 3-back task was observed following both 50 Hz and Ind iTBS conditions. These findings highlight the critical importance of frequency in the parameter space of iTBS. Tailored stimulation parameters appear more efficacious than standard paradigms in neurophysiological and mood changes. This novel approach presents a promising option and benefits may extend to clinical applications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.