Evidence map›Paper›PMID 30251566›Full record

ReviewCell transplantation2018

Cerebral Small Vessel Disease.

Qian Li, Yang Yang, Cesar Reis, Tao Tao, Wanwei Li, Xiaogang Li, John H Zhang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
165citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

165 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Article
  9. The Roles of EETs in Neurological Disorders.CNS neuroscience & therapeutics · 2026
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105 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qian Li1 Department of Pediatrics, The Third Affiliated Hospital & Field Surgery Institution, Army Medical University, Chongqing, China.
Yang Yang2 Department of Neurology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Cesar Reis3 Department of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Tao Tao2 Department of Neurology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
Wanwei Li1 Department of Pediatrics, The Third Affiliated Hospital & Field Surgery Institution, Army Medical University, Chongqing, China.
Xiaogang Li2 Department of Neurology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
John H Zhang3 Department of Physiology and Pharmacology, Loma Linda University School of Medicine, Loma Linda, CA, USA.ORCID 0000-0002-4319-4285

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral small vessel disease (CSVD) is composed of several diseases affecting the small arteries, arterioles, venules, and capillaries of the brain, and refers to several pathological processes and etiologies. Neuroimaging features of CSVD include recent small subcortical infarcts, lacunes, white matter hyperintensities, perivascular spaces, microbleeds, and brain atrophy. The main clinical manifestations of CSVD include stroke, cognitive decline, dementia, psychiatric disorders, abnormal gait, and urinary incontinence. Currently, there are no specific preventive or therapeutic measures to improve this condition. In this review, we will discuss the pathophysiology, clinical aspects, neuroimaging, progress of research to treat and prevent CSVD and current treatment of this disease.

Indexed as

ArteriolosclerosisCerebral Amyloid AngiopathyCerebral Small Vessel DiseasesHumansMagnetic Resonance ImagingPlatelet Aggregation InhibitorsStrokeTissue Plasminogen ActivatorWhite MatterPlatelet Aggregation InhibitorsTissue Plasminogen Activatorarteriolosclerosiscerebral amyloid angiopathyCerebral small vessel diseasedementiaMRIneuroimagingstroke syndrome

Identifiers

PMID30251566
PMCPMC6300773

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.