Evidence map›Paper›PMID 30251483›Full record

ArticleJournal of biomedical optics2018

Noncontact speckle contrast diffuse correlation tomography of blood flow distributions in tissues with arbitrary geometries.

Siavash Mazdeyasna, Chong Huang, Mingjun Zhao, Nneamaka B Agochukwu, Ahmed A Bahrani, Lesley Wong, Guoqiang Yu

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Siavash MazdeyasnaUniversity of Kentucky, F. Joseph Halcomb III, M.D. Department of Biomedical Engineering, Lexington,, United States.
Chong HuangUniversity of Kentucky, F. Joseph Halcomb III, M.D. Department of Biomedical Engineering, Lexington,, United States.
Mingjun ZhaoUniversity of Kentucky, F. Joseph Halcomb III, M.D. Department of Biomedical Engineering, Lexington,, United States.
Nneamaka B AgochukwuUniversity of Kentucky, Division of Plastic Surgery, Lexington, Kentucky, United States.
Ahmed A BahraniUniversity of Kentucky, F. Joseph Halcomb III, M.D. Department of Biomedical Engineering, Lexington,, United States.
Lesley WongUniversity of Kentucky, Division of Plastic Surgery, Lexington, Kentucky, United States.
Guoqiang YuUniversity of Kentucky, F. Joseph Halcomb III, M.D. Department of Biomedical Engineering, Lexington,, United States.

Funding

Noninvasive Noncontact High-Density Optical Imaging of Neonatal Intraventricular HemorrhageR01HD101508 · NICHD · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2024
$2.7M
Time-resolved laser speckle contrast imaging of resting-state functional connectivity in neonatal brainR42MH135825 · NIMH · BIOPTICSTECHNOLOGY, LLC · PI YU, GUOQIANG · 2023 to 2025
$2.1M
Development of a Wearable Fluorescence Imaging Device for IntraoperativeIdentification of Brain TumorsR42CA243600 · NCI · BIOPTICSTECHNOLOGY, LLC · PI YU, GUOQIANG · 2023 to 2025
$2.0M
Perioperative Diffuse Optical Imaging of Tissue Blood Flow and Oxygenation for Optimization of Mastectomy Skin Flap ViabilityR01EB028792 · NIBIB · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2024
$1.9M
Diffuse Optical Monitoring of Head and Neck Tumor TherapyR01CA149274 · NCI · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2010 to 2014
$1.4M
High-density optical tomography of cerebral blood flow and metabolism in small animalsR41NS122722 · NINDS · BIOPTICSTECHNOLOGY, LLC · PI YU, GUOQIANG · 2021 to 2022
$688k
Continuous and Longitudinal Monitoring of Cerebral Blood Flow and Metabolism in Freely Moving RodentsR56NS117587 · NINDS · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2020
$613k
A Multiscale Multimodal Diffuse Optical Device for Early Detection of Preclinical Alzheimer’s DiseaseR21HD091118 · NICHD · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2018 to 2019
$568k
Non-contact Diffuse Optical Assessment of Pressure Ulcer and TherapyR21AR062356 · NIAMS · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2012 to 2013
$350k
Development of a Wearable Fluorescence Imaging Device for Intraoperative Identification of Brain TumorsR41CA243600 · NCI · BIOPTICSTECHNOLOGY, LLC · PI YU, GUOQIANG · 2019 to 2019
$210k
NCI NIH HHS R01 CA149274NCI NIH HHS R41 CA243600NCI NIH HHS R42 CA243600NIAMS NIH HHS R21 AR062356NIBIB NIH HHS R01 EB028792NICHD NIH HHS R01 HD101508NICHD NIH HHS R21 HD091118NIMH NIH HHS R42 MH135825NINDS NIH HHS R41 NS122722NINDS NIH HHS R56 NS117587
6 · The paper itself

Abstract

A noncontact electron multiplying charge-coupled-device (EMCCD)-based speckle contrast diffuse correlation tomography (scDCT) technology has been recently developed in our laboratory, allowing for noninvasive three-dimensional measurement of tissue blood flow distributions. One major remaining constraint in the scDCT is the assumption of a semi-infinite tissue volume with a flat surface, which affects the image reconstruction accuracy for tissues with irregular geometries. An advanced photometric stereo technique (PST) was integrated into the scDCT system to obtain the surface geometry in real time for image reconstruction. Computer simulations demonstrated that a priori knowledge of tissue surface geometry is crucial for precisely reconstructing the anomaly with blood flow contrast. Importantly, the innovative integration design with one single-EMCCD camera for both PST and scDCT data collection obviates the need for offline alignment of sources and detectors on the tissue boundary. The in vivo imaging capability of the updated scDCT is demonstrated by imaging dynamic changes in forearm blood flow distribution during a cuff-occlusion procedure. The feasibility and safety in clinical use are evidenced by intraoperative imaging of mastectomy skin flaps and comparison with fluorescence angiography.

Indexed as

FemaleForearmHumansImage Interpretation, Computer-AssistedMastectomyNecrosisRegional Blood FlowSurgical FlapsTomography, Opticalblood flow distributiondiffuse optical imagingmastectomy skin flap necrosistissue surface geometry

Identifiers

PMID30251483
PMCPMC6183314

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.