Evidence map›Paper›PMID 30251216›Full record

ArticleJournal of general internal medicine2018

County and Physician Variation in Benzodiazepine Prescribing to Medicare Beneficiaries by Primary Care Physicians in the USA.

Donovan T Maust, Lewei A Lin, Frederic C Blow, Steven C Marcus

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Donovan T MaustDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA. maustd@umich.edu.
Lewei A LinDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Frederic C BlowDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Steven C MarcusSchool of Social Practice and Policy, University of Pennsylvania, Philadelphia, PA, USA.
University of Michigan–Ann Arbor · USUniversity of Pennsylvania · US

Funding

Leveraging large-scale national data to understand, reduce, and prevent benzodiazepine-related harms among older adultsR01DA045705 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MAUST, DONOVAN T · 2018 to 2022
$2.5M
Preventable Hospitalization in Dementia: The Impact of Neuropsychiatric SymptomsK08AG048321 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MAUST, DONOVAN T · 2014 to 2017
$700k
NIA NIH HHS K08 AG048321NIDA NIH HHS R01 DA045705
6 · The paper itself

Abstract

backgroundPhysicians widely prescribe benzodiazepines (BZD) despite well-recognized harms.

objectiveTo determine county and provider characteristics that predict high-intensity BZD prescribing by primary care physicians (PCPs) to Medicare beneficiaries.

designCross-sectional analysis of the 2015 Medicare Part D Public Use Files (PUF). SUBJECTS: n = 122,054 PCPs who prescribed 37.3 billion medication days. MAIN MEASURES: Primary outcome was intensity of BZD prescribing (days prescribed/total medication days) at the county- and physician levels. PCP and county characteristics were derived from the Part D PUF, Area Health Resources Files, and County Health Rankings. Logistic regression determined the characteristics associated with high-intensity (top quartile) BZD prescribing. KEY

resultsBeneficiaries were prescribed over 1.2 billion days of BZD in 2015, accounting for 2.3% of all medication days prescribed in Part D. Top quartile counties had 3.1 times higher BZD prescribing than the lowest (3.4% vs. 1.1%; F = 3293.8, df = 3, p < 0.001). Adjusting for county-level demographics and health care system characteristics (including supply of mental health providers), counties with more adults with at least some college had lower odds of high-intensity prescribing (per 5% increase, adjusted odds ratio [AOR] 0.80, 99% confidence interval (CI) 0.73-0.87, p < 0.001), as did higher income counties (per US$1000 increase, AOR 0.93, CI 0.91-0.95, p < 0.001). Top quartile PCPs prescribed at 6.5 times the rate of the bottom (3.9% vs. 0.6%; F = 63,910.2, df = 3, p < 0.001). High-intensity opioid prescribing (AOR 4.18, CI 3.90-4.48, p < 0.001) was the characteristic most strongly associated with BZD prescribing.

conclusionsBZD prescribing appears to vary across counties and providers and is related to non-patient characteristics. Further work is needed to understand how such non-clinical factors drive variation.

Indexed as

AgedAged, 80 and overBenzodiazepinesCross-Sectional StudiesFemaleHospitals, CountyHumansMaleMedicare Part DPhysicians, Primary CarePractice Patterns, Physicians'United StatesBenzodiazepinesanxietybenzodiazepineinsomniaphysicianprimary care

Identifiers

PMID30251216
PMCPMC6258632
OpenAlexW2892772098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.