ReviewCurrent neurology and neuroscience reports2018
Asymptomatic Carotid Stenosis: Intervention or Best Medical Therapy?
Review in Current neurology and neuroscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- The Efficacy of Transcarotid Artery Revascularization With Flow Reversal System Compared to Carotid Endarterectomy: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2021Pooled it
- A Comparative Analysis of Short-Term Outcomes of Off Pump Coronary Artery Bypass Grafting Alone or Simultaneous Cerebral Revascularization: A Single-Center Retrospective Study.Clinical cardiology · 2026Article
- Identification of key genes and regulatory networks associated with atherosclerotic carotid artery stenosis through comprehensive bioinformatics analysis and machine learning.European journal of medical research · 2025Article
- Carotid Stenosis and Stroke: Medicines, Stents, Surgery-"Wait-and-See" or Protect?Thrombosis and haemostasis · 2024Article
- Outcomes of carotid endarterectomy: Insights from a single-center retrospective cohort study.Saudi medical journal · 2024Article
- Review
- Virtual reality psychological intervention helps reduce preoperative anxiety in patients undergoing carotid artery stenting: a single-blind randomized controlled trial.Frontiers in psychology · 2023Article
- Association between platelet lymphocyte ratio and neutrophil lymphocyte ratio and clinical outcomes following carotid endarterectomy.Jornal vascular brasileiro · 2023Article
- Inverse material parameter estimation of patient-specific finite element models at the carotid bifurcation: The impact of excluding the zero-pressure configuration and residual stress.International journal for numerical methods in biomedical engineering · 2023Article
- Ex Vivo Study Using Diffusion Tensor Imaging to Identify Biomarkers of Atherosclerotic Disease in Human Cadaveric Carotid Arteries.Arteriosclerosis, thrombosis, and vascular biology · 2022Article
- Stroke incidence between stenting and endarterectomy for asymptomatic carotid artery stenosis.Annals of medicine and surgery (2012) · 2022Article
- Spectral segmentation and radiomic features predict carotid stenosis and ipsilateral ischemic burden from DECT angiography.Diagnostic and interventional radiology (Ankara, Turkey) · 2022Article
- Correlation between Carotid Stenosis Degree and Blood Pressure Variability in Patients with Carotid Stenosis.Computational and mathematical methods in medicine · 2022Article
- A novel integrated angioscope-laser system for atherosclerotic carotid artery occlusion: Feasibility and techniques.Frontiers in surgery · 2022Article
- Macrophage-Hypoxia-Inducible Factor-1α Signaling in Carotid Artery Stenosis.The American journal of pathology · 2021Article
- [Less is more in cardiology and angiology].Der Internist · 2021Review
- Article
- lncRNA PCA3 Suppressed Carotid Artery Stenosis and Vascular Smooth Muscle Cell Function via Negatively Modulating the miR-124-3p/ITGB1 Axis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- Carotid atherosclerotic disease: A systematic review of pathogenesis and management.Brain circulationReview
- Deregulated Long Non-Coding RNA HCG11 in Cerebral Atherosclerosis Serves as a Biomarker to Predict the Risk of Cerebrovascular Events.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewProvide a current overview regarding the optimal strategy for managing patients with asymptomatic carotid artery stenosis. RECENT
findingsCarotid endarterectomy (CEA) and carotid artery stenting (CAS) reduce long-term stroke risk in asymptomatic patients. However, CAS is associated with a higher risk of peri-procedural stroke. Improvements in best medical therapy (BMT) have renewed uncertainty regarding the extent to which results from older randomised controlled trials (RCTs) comparing outcomes following carotid intervention can be generalised to modern medical practise. 'Average surgical risk' patients with an asymptomatic carotid artery stenosis of 60-99% and increased risk of late stroke should be considered for either CEA or CAS. In patients deemed 'high risk' for surgery, CAS is indicated. Use of an anti-platelet, anti-hypertensive and statin, with strict glycaemic control, is recommended. Results from ongoing large, multicentre RCTs comparing CEA, CAS and BMT will provide clarity regarding the optimal management of patients with asymptomatic carotid artery stenosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.