Evidence map›Paper›PMID 30250972›Full record

ReviewHistochemistry and cell biology2018

Monoamines in the enteric nervous system.

Winfried Neuhuber, Jürgen Wörl

Abstract readReview
PubMed Publisher
In one paragraph

Review in Histochemistry and cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  11. In focus in HCB.Histochemistry and cell biology · 2020
    Article
  12. Article
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  14. Kidney dopamine DAmerican journal of physiology. Renal physiology · 2019
    Article
  15. In focus in HCB.Histochemistry and cell biology · 2018
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Winfried NeuhuberInstitute of Anatomy, Friedrich-Alexander-University Erlangen-Nürnberg, Krankenhausstraße 9, 91054, Erlangen, Germany. winfried.neuhuber@fau.de.ORCID http://orcid.org/0000-0003-1387-4682
Jürgen WörlInstitute of Anatomy, Friedrich-Alexander-University Erlangen-Nürnberg, Krankenhausstraße 9, 91054, Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

DFG NE 534/3-1
6 · The paper itself

Abstract

Recent advances in neurogastroenterology have extended and refined our knowledge on the roles monoamines play in physiology and pathophysiology of the gastrointestinal tract. The catecholamine noradrenaline, as the primary transmitter of postganglionic sympathetic neurons, orchestrates motility and secretory reflexes and controls arterial perfusion as well as immune functions. The catecholamine dopamine is produced by a subpopulation of enteric neurons which possibly use it as transmitter. Serotonin, largely produced by enterochromaffin cells and to a small extent by enteric neurons profoundly affects gut motility, enteric neuron development and is also involved in immunomodulation. However, its mode of action and the relative contribution of non-neuronal versus neuronal serotonin was recently subject to debate again. Histamine, although entirely of non-neuronal origin, is pivotal for gastrointestinal neuroimmunomodulation besides its paracrine effect in gastric HCl production.

Indexed as

AminesCatecholaminesEnteric Nervous SystemHumansSerotoninAminesCatecholaminesSerotoninCatecholaminesDopamineEnteric neuronsExtrinsic innervationHistamineNoradrenalineSerotonin

Identifiers

PMID30250972
OpenAlexW2894023355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.