Evidence map›Paper›PMID 30250928›Full record

ArticleMolecular & cellular oncology2018

CDC25 as a common therapeutic target for triple-negative breast cancer - the challenges ahead.

Eldad Zacksenhaus, Jeff C Liu, Letizia Granieri, Ioulia Vorobieva, Dong-Yu Wang, Ronak Ghanbari-Azarnier, Huiqin Li, Amjad Ali, Philip E D Chung, YoungJun Ju and 2 more

Abstract read
In one paragraph

Article in Molecular & cellular oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Effect ofMicroorganisms · 2023
    Article
  3. Article
  4. TargetingCancers · 2021
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eldad ZacksenhausToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.
Jeff C LiuToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.
Letizia GranieriToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.
Ioulia VorobievaToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.
Dong-Yu WangToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.
Ronak Ghanbari-AzarnierToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.
Huiqin LiToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.
Amjad AliToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.
Philip E D ChungToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.
YoungJun JuToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.
Zhe JiangToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.
Mariusz ShresthaToronto General Research Institute - University Health Network, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dual phosphatase CDC25 has recently been identified as a target for diverse triple-negative breast cancers including

Indexed as

CDC25 inhibitorsp53PTENRB1therapyTriple negative breast cancer

Identifiers

PMID30250928
PMCPMC6149702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.