Evidence map›Paper›PMID 30250751›Full record

ArticleVirus evolution2018

Inferring the age difference in HIV transmission pairs by applying phylogenetic methods on the HIV transmission network of the Swiss HIV Cohort Study.

Katharina Kusejko, Claus Kadelka, Alex Marzel, Manuel Battegay, Enos Bernasconi, Alexandra Calmy, Matthias Cavassini, Matthias Hoffmann, Jürg Böni, Sabine Yerly and 6 more

Open access · goldAbstract read
In one paragraph

Article in Virus evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Katharina KusejkoDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zürich, Rämistrasse 100, Zürich, Switzerland.ORCID 0000-0002-4638-1940
Claus KadelkaDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zürich, Rämistrasse 100, Zürich, Switzerland.
Alex MarzelDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zürich, Rämistrasse 100, Zürich, Switzerland.
Manuel BattegayDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Petersgraben 4, CH-4031 Basel; University of Basel, Petersplatz 1, Basel, Switzerland.
Enos BernasconiDivision of Infectious Diseases, Regional Hospital Lugano, Via Tesserete 46, Lugano, Switzerland.
Alexandra CalmyLaboratory of Virology and Division of Infectious Diseases, Genève University Hospital, Rue Gabrielle-Perret-Gentil 4, CH-1205 Genève; University of Genève, 24 rue du Général-Dufour, Genève, Switzerland.
Matthias CavassiniDivision of Infectious Diseases, Lausanne University Hospital, Rue du Bugnon 46, Lausanne, Switzerland.
Matthias HoffmannDivision of Infectious Diseases, Cantonal Hospital St Gallen, Rorschacher Strasse 95, St. Gallen, Switzerland.
Jürg BöniInstitute of Medical Virology, University of Zürich, Winterthurerstrasse 190, Zürich, Switzerland.
Sabine YerlyLaboratory of Virology and Division of Infectious Diseases, Genève University Hospital, Rue Gabrielle-Perret-Gentil 4, CH-1205 Genève; University of Genève, 24 rue du Général-Dufour, Genève, Switzerland.
Thomas KlimkaitMolecular Virology, Department of Biomedicine, University of Basel, Petersplatz 10, Basel, Switzerland.
Matthieu PerreauDivision of Infectious Diseases, Lausanne University Hospital, Rue du Bugnon 46, Lausanne, Switzerland.
Andri RauchClinic for Infectious Diseases, Bern University Hospital, Freiburgstrasse 18, Bern; University of Bern, Hochschulstrasse 6, CH-3012 Bern, Switzerland.
Huldrych F GünthardDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zürich, Rämistrasse 100, Zürich, Switzerland.
Roger D KouyosDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Zürich, Rämistrasse 100, Zürich, Switzerland.ORCID 0000-0002-9220-8348
Swiss HIV Cohort Study
University of Zurich · CHUniversity of Lausanne · CHUniversity of Geneva · CHUniversity of Basel · CHKantonsspital St. Gallen · CHUniversity of Bern · CHOspedale regionale di Lugano · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-mixing patterns are of key importance for understanding the dynamics of human immunodeficiency virus (HIV)-epidemics and target public health interventions. We use the densely sampled Swiss HIV Cohort Study (SHCS) resistance database to study the age difference at infection in HIV transmission pairs using phylogenetic methods. In addition, we investigate whether the mean age difference of pairs in the phylogenetic tree is influenced by sampling as well as by additional distance thresholds for including pairs. HIV-1

Indexed as

age structurecophenetic distanceHIVphylogeniessampling

Identifiers

PMID30250751
PMCPMC6143731
OpenAlexW2892192637

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.