Evidence map›Paper›PMID 30250568›Full record

ArticleOncology letters2018

Liriodenine enhances radiosensitivity in esophageal cancer ECA-109 cells by inducing apoptosis and G

Gang Wu, Guangzong Chen, Jialiang Zhou, Hongcheng Zhu, Jianjun Chu, Fuzheng Zhang

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Gang WuDepartment of Radiation Oncology, The Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu 214062, P.R. China.
Guangzong ChenDepartment of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Jialiang ZhouDepartment of Radiation Oncology, The Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu 214062, P.R. China.
Hongcheng ZhuDepartment of Radiation Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Jianjun ChuDepartment of Radiation Oncology, The Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu 214062, P.R. China.
Fuzheng ZhangDepartment of Radiation Oncology, The Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu 214062, P.R. China.
Wuxi Fourth People's Hospital · CNJiangsu Province Hospital · CNJiangnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At present, chemotherapy and radiotherapy represent the primary modalities of treatment for patients with unresectable esophageal squamous cell carcinoma (ESCC). However, the outcome of patients remains poor owing to radioresistance. The present study aimed to determine the radiosensitizing effect of liriodenine, an aporphine alkaloid derived from

Indexed as

apoptosisesophageal squamous cell carcinomaG2/M arrestliriodenineradiotherapy

Identifiers

PMID30250568
PMCPMC6144705
OpenAlexW2885433733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.