Evidence map›Paper›PMID 30250029›Full record

ArticleNature communications2018

Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge.

Shuying Yi, Jing Zhai, Rui Niu, Guangming Zhu, Meixiang Wang, Jianguo Liu, Hua Huang, Yaping Wang, Xiuli Jing, Li Kang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 66 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
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  6. Association of theInternational journal of molecular sciences · 2025
    Article
  7. Review
  8. Review
  9. Respiratory Diseases Associated With Organic Dust Exposure.The journal of allergy and clinical immunology. In practice · 2024
    Review
  10. Article
  11. Review
  12. Eosinophil Phenotypes Are Functionally Regulated by Resolvin D2 during Allergic Lung Inflammation.American journal of respiratory cell and molecular biology · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Frontiers in microbiology · 2023
    Article
  17. Chemokines and chemokine receptors in allergic rhinitis: from mediators to potential therapeutic targets.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Shuying YiInstitute of Immunology, Taishan Medical University, Taian, 271000, Shandong, China.
Jing ZhaiSchool of Basic Medical Sciences, Taishan Medical University, Taian, 271000, Shandong, China.
Rui NiuInstitute of Immunology, Taishan Medical University, Taian, 271000, Shandong, China.
Guangming ZhuInstitute of Immunology, Taishan Medical University, Taian, 271000, Shandong, China.
Meixiang WangShanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China.
Jianguo LiuInstitute of Immunology, Taishan Medical University, Taian, 271000, Shandong, China.
Hua HuangInstitute of Immunology, Taishan Medical University, Taian, 271000, Shandong, China.
Yaping WangInstitute of Immunology, Taishan Medical University, Taian, 271000, Shandong, China.
Xiuli JingInstitute of Immunology, Taishan Medical University, Taian, 271000, Shandong, China.
Li KangInstitute of Immunology, Taishan Medical University, Taian, 271000, Shandong, China.
Wengang SongInstitute of Immunology, Taishan Medical University, Taian, 271000, Shandong, China.
Yufang ShiInstitute of Health Sciences, Shanghai Institutes for Biological Sciences, Shanghai, 200031, China.ORCID http://orcid.org/0000-0001-9716-2126
Hua TangInstitute of Immunology, Taishan Medical University, Taian, 271000, Shandong, China. tanghuazhang218@163.com.
Taishan Medical University · CNShanghai Public Health Clinical Center · CNShanghai Institutes for Biological Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophil infiltration, a hallmark of allergic asthma, is essential for type 2 immune responses. How the initial eosinophil recruitment is regulated by lung dendritic cell (DC) subsets during the memory stage after allergen challenge is unclear. Here, we show that the initial eosinophil infiltration is dependent on lung cDC1s, which require nitric oxide (NO) produced by inducible NO synthase from lung CD24

Indexed as

AllergensAnimalsAsthmaChemokine CCL17Chemokine CCL22Chronic DiseaseDendritic CellsDisease Models, AnimalEosinophilsFemaleHumansLungMiceMice, Inbred C57BLNitric OxideNitric Oxide Synthase Type IIAllergensCcl17 protein, mouseCcl22 protein, mouseChemokine CCL17Chemokine CCL22Nitric OxideNitric Oxide Synthase Type IINos2 protein, mousePapainTgfb1 protein, mouseTransforming Growth Factor beta1

Identifiers

PMID30250029
PMCPMC6155158
OpenAlexW2890925318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.